CLINICAL ROLE -
March 28th 2025
Vitamin E intake, specifically α-tocopherol, may reduce the development of peanut allergies and anaphylaxis in newborns.
March 14th 2025
The authors note that further research is needed to clarify cost-effectiveness, long-term adherence, and psychosocial impacts of oral immunotherapy.
March 12th 2025
Eculizumab, a humanized monoclonal antibody, was first approved for adults with generalized myasthenia gravis in 2017.
March 7th 2025
The cancers linked with per- and polyfluoroalkyl substance (PFAS) exposure included nonastrocytoma gliomas, acute myeloid leukemia, and Wilms tumors.
The treatment is currently undergoing evaluation in an investigational preclinical program and is projected to be in human trials in 2026.
The Impact of Pharmacists and Pharmacy Technicians in Recognizing and Responding to Human Trafficking (Pharmac...
2.0 Credits / Human Trafficking, Law
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Ensuring Pharmacy Technicians’ Proficiency in Risk Evaluation and Mitigation Strategies
1.0 Credit / Law, Pain Management, Opioids
Study Finds Associations Between Chronic Pain and Anxiety, Depressive Symptoms in Youths
The authors urge that screening, prevention, and treatment of anxiety and depression should be important health care priorities for youth who have chronic pain.
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FDA Grants Rare Pediatric Disease Designation to NS-050/NCNP-03 to Treat Muscle Wasting Disease
NS-050/NCNP-03 is being developed to aid individuals with confirmed gene mutations that are treatable with exon 50 skipping therapy.
Obesity, Emaciated BMI Associated With Poor Prognosis in Pediatric B-Cell Non-Hodgkin Lymphoma
Surprisingly, those with overweight BMI at diagnosis did not have a poor prognosis.
Apremilast Now Available to Treat Pediatrics With Plaque Psoriasis
Pediatric patients weighing 20 kg to <50 kg should take 20 mg of apremilast twice daily and children weighing at least 50 kg should take 30 mg twice daily.
Study: Lack of Nutritional Value Found in Almost 60% of US Baby Food
Pharmacists can help caregivers by recommending a healthy balanced diet containing high vitamin D intake and supplementation when needed.
Help Prepare Families for Back-to-School Season
Remind parents that routine exams, immunizations, and nutrition are crucial to helping children succeed.
FDA Grants Rare Pediatric Disease Designation to SAT-3247 to Treat Duchenne Muscular Dystrophy
The commencement of the phase 1 clinical trial of SAT-3247 is expected in Q3 of 2024.
ABS-0871 Receives FDA Orphan Drug Designation for Treatment of Charcot-Marie-Tooth Disease 2C
The FDA also granted rare pediatric disease designation for the drug.
Back-to-School Season Is Here
Global Immunization Coverage Lacking Since COVID-19 Pandemic, Especially in Children
Immunization rates have not returned to pre-pandemic levels, leaving millions of children and infants at risk for measles or diphtheria, tetanus, and pertussis.
FDA Extends Palforzia Approval to Children 1 to 3 Years Old With Peanut Allergy
The approval marks the first oral immunotherapy treatment to mitigate allergic reactions, including anaphylaxis.
Indole-3-Propionic Acid Shows Long-Term Protection Against Asthma
The molecule can be a potential treatment that counters effects of early-life antibiotics, which can impact the gut microbiota and increase the risk of childhood atopy and asthma.
FDA Approves Cerliponase Alfa for Expanded Indication of CLN2 Disease
In April 2017, the drug was approved to treat the slow loss of the ability to walk for symptomatic patients aged 3 and older who had Batten disease.
Notable Comorbidities and Unmet Needs in Pediatric Asthma
The authors emphasize that clinical research should focus on real-world difficulties, and pediatric asthma control should be seen as a health care priority.
Researchers Identify Links Between Gut Microbiome and Autism, Potentially Paving the Way for New Diagnostics
Unique gut flora were found in children with autism spectrum disorder (ASD).
Study Finds Gender and Racial Disparities in Youth Psychiatric Inpatient Admissions
The authors emphasize that these findings suggest a need for targeted resources that help reduce boarding and promote equitable access to care.
Higher COVID-19 Vaccination Rates May Provide Protection Against Symptomatic Asthma in Pediatric Patients
Higher vaccination rates were associated with less prevalent asthmatic symptoms, but additional research is needed to confirm these findings.
Dupilumab Helps Pediatric Patients With Eosinophilic Esophagitis Achieve Histologic Remission
In 2 different dose groups, the majority of patients with eosinophilic esophagitis aged 1 to 11 achieved histologic remission at week 16 compared with patients treated with placebo.
Colder Temperatures May Worsen Asthma Symptoms in Pediatric Patients
However, more research is needed to effectively integrate this biomarker into individualized asthma management strategies for pediatric patients.
Children With Asthma on Medicaid Less Likely to Receive Specialist Care
The findings show that the largest gaps are among pediatric patients with persistent asthma.
Xolair From Genentech
Study Finds Relative Age Effect on ADHD Diagnosis and Prescription of Medication in Children
Autism spectrum disorder was also evaluated in the analysis, but further research is required to determine a possible association with relative age effect.
E-Cigarette Exposure May Increase Risk of Atopic Dermatitis in Children
Secondhand exposure to e-cigarette smoke may increase risk of pediatric atopic dermatitis in children.
Children Exposed to Weed and Tree Pollen in Urban Areas May Experience Increased Risk of Asthma Onset
The study results also found that exposure to tree canopy area may protect children from asthma development; however, efficacy decreased as weed pollen exposure increased.
Trametinib Demonstrates Potential as a First-Line Treatment for Pediatric Patients with JMML
Trametinib may become an alternative treatment to hematopoietic stem cell transplantation in patients with relapsed or refractory juvenile myelomonocytic leukemia (JMML).
FDA Approves Dapagliflozin For Pediatric Patients With Type 2 Diabetes
The indication is for the improvement of glycemic control in pediatric patients aged 10 and older with type 2 diabetes and comes after positive results from the phase 3 T2NOW clinical trial.
Pharmacists Play Crucial Role in Dupilumab Treatment for Infants, Young Children With Atopic Dermatitis
Parents and caregivers sometimes have concerns about their children receiving these injections, but researchers and experts assure that the FDA-approved biologic is safe and effective in young populations.
FDA Approves Sarilumab for Active Polyarticular Juvenile Idiopathic Arthritis
Polyarticular juvenile idiopathic arthritis is a form of arthritis that affects multiple joints at one time.
Study Finds Alterations in Functional Connectivity of Brain Regions in Adolescents With Internet Addiction
The authors noted that these networks have a significant role in intellectual ability, physical coordination, working memory, emotional processing, and overall mental health.
Educate Caregivers About Proper OTC Cold and Cough Medications for Children
Approximately 40% of caregivers make dosing errors when administering liquid medication to children.