Sleep

Pitolisant is now the first and only FDA-approved nonscheduled treatment for cataplexy in pediatric and adult patients with narcolepsy.

The authors suggested that future research investigate emerging blood-based biomarkers and explore temporal associations between sleep duration and Alzheimer disease biomarker changes.

Insufficient sleep significantly impacts life expectancy, highlighting the need to prioritize quality rest for better health and longevity.

GLP-1 receptor agonists expand treatment options for diabetes, weight loss, and more, showing promise in heart failure, kidney disease, and neuroprotection.

Moderate to severe obstructive sleep apnea significantly increases the risk of cerebral microbleeds.

Research highlights the impact of sleep disturbances and vasomotor symptoms (VMS) on HRQoL in women transitioning to menopausal period, emphasizing the need for effective management.

Explore effective strategies for safely discontinuing benzodiazepines and sedative-hypnotics, addressing risks and enhancing patient care in older adults.

In 2 clinical trials, oveporexton shows promise in treating narcolepsy type 1 (NT1), paving the way for potential FDA approval.

In the double-blind portion of Vibrance-1, alixorexton improved wakefulness while eliciting broad benefits in patient-reported outcomes.

Melatonin supplementation could improve oxidative DNA damage repair capacity among night shift workers.

Health care professionals, particularly pharmacists, can recommend that patients take over-the-counter supplements, such as melatonin, to facilitate REM sleep.

Age, frequent snoring, hypertension, and poor glycemic control are associated with excessive daytime sleepiness.

The new approval continues to expand the therapeutic potential of GLP-1 medications such as tirzepatide, now being deemed effective in patients with obstructive sleep apnea.

Treatment for RLS includes lifestyle modifications, medication, and in some cases, non-drug therapies, aiming to reduce symptoms and improve sleep and daytime functioning.

Tryptophan, found in turkey and other foods, affects serotonin and melatonin production.

Insomnia exhibits a dose-response relationship with AF recurrence, indicating that an increased number of insomnia symptoms is associated with heightened probability of AF recurrence.

Low levels of vitamin D was linked with increased obstructive Apnea-Hypopnea Index scores.

Patients aged 7 years and older can now be treated for their cataplexy or excessive daytime sleepiness with the extended-release oral formulation.

Treatment with tirzepatide has led not only to significant reductions in excess body weight, but also improvements in blood pressure and reduction of inflammatory markers.

AI-enabled remote cardiac monitoring offers continuous data on heart activity, allowing for the early detection of arrhythmias, optimized treatment timing, and improved sleep-related heart health management.

Poor sleep quality is directly related to mortality risk before adjusting for lifestyle or health-related factors, and dementia was noticeably linked to mortality risk in older White males.

Pharmacists can help identify potential drug-drug interactions and adverse reactions, and advise patients when to seek further treatment

The ADA Clinical Practice Recommendations added sleep assessment for precision medicine in type 2 diabetes, supporting the wealth of information surrounding the association.

The findings show that those with higher plasma homocysteine concentrations experienced more sleep apnea events per hour compared with those with lower concentrations.