CLINICAL ROLE -
Ashley Gallagher is an assistant editor at Pharmacy Times®. She graduated from St. Bonaventure University in 2020 in journalism and mass communications. Previously, she worked as a pharmacy technician for a retail chain.
Pfizer Begins Phase 2/3 Study of COVID-19 Treatment Paxlovid in Children
The medication is the first oral therapy specifically to treat the virus evaluated in a pediatric clinical trial.
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Smoking in Underserved Communities Is Nearly Double the National Rate, Study Results Show
Prevalence is also linked to mental health conditions and substance use disorders, according to analysis.
Heart Defects Linked to Higher Risk of Severe COVID-19 Illness, Study Results Show
These individuals, who were also more likely to require treatment in the intensive care unit, should get their vaccines and booster shots, investigators say.
Migraines Can Affect Ability to Work, Study Results Show
Headache disorders most affect the ability to do physical labor, decision-making skills, and memory, investigators from the University of Copenhagen say.
Study: Additional Doses of COVID-19 Vaccine Benefit Immunocompromised Individuals
Investigators advise third short for patients with weakened immune system, especially organ transplant recipients.
Study: Women With Migraines Show Higher Risk of Pregnancy Complications
Although the risks are still, individuals with a history of migraines should be aware of and consult with their physicians, investigators say.
Gilead’s Trodelvy Meets Primary Endpoint for Late-Line HR+/HER2- Metastatic Breast Cancer
Phase 3 TROPiCS-02 study continues to follow patients for overall survival, a key secondary endpoint.
Study: 2 Doses of Pfizer COVID-19 Vaccine Provide Protection for 4 Months in Adolescents
Effectiveness is estimated at approximately 91% against any SARS-CoV-2 infection and approximately 85% effective against asymptomatic infection, analysis results show.
E-Cigarette Use Increases Odds of Prediabetes, Study Results Show
Important evidence about the health effects of e-cigarettes can help shape public health best practices in the United States, the findings of an analysis suggest.
FDA Grants Breakthrough Therapy Designation to Pfizer’s RSV Vaccine Candidate
The decision is informed by the results of a phase 2b proof-of-concept study that assessed the immunogenicity and safety of the drug in healthy pregnant women and their infants.
CVS Health Report Focuses on Overall Drug Trends in 2021
The health care company’s analysis evaluates non-specialty and specialty drugs, biosimilars, medication affordability, and the cost of administering COVID-19 vaccines.
Health Care Settings Can Benefit From Serosurveys to Design Infection Control Practices
Study results show immunoglobulin G antibodies were detected in 13 of 382 individuals in the first phase and 71 of 168 in the second, with age and vaccination status contributing factors.
5 Key Sessions at the American Pharmacists Association Annual Meeting and Exposition
The annual conference includes presentations with educational opportunities related to community pharmacies, health system pharmacies, pharmacy law, public health, and more.
Benefits of Empagliflozin Proves Greater Than Placebo for Those With Acute Heart Failure
Study results show that individuals hospitalized for acute heart failure are 36% more likely to experience clinical benefit over 90 days if initiated on the drug following stabilization.
Clinical Review Shows Insight on Immune Response of Pain Management Drugs
The findings highlight the potential of acetaminophen, non-steroidal anti-inflammatory drugs, and opioid analgesics to treat infectious diseases.
FDA Approves 10-mg Naloxone Injection to Treat Exposure to Ultra-Potent Weaponized Opioids
Kaléo’s product has received fast-track designation for US military personnel facing this threat on the battlefield.
FDA Accepts Application for Opdivo Plus Chemotherapy for Treatment of NSCLC
Acceptance is based on CheckMate -816 trial results where the agency granted priority review status to the Bristol Myers Squibb drug and assigned a PDUFA goal date of July 13, 2022.
Study: Several FDA-Approved Drugs Help Combat COVID-19 Delta Variant
Investigators at Penn State find that these medications inhibit certain viral enzymes called proteases that are essential for SARS-CoV-2 replication in infected human cells.
Study: Evolocumab Shows a Higher Reduction in LDL-C Than Alirocumab
At week 4, there was about a 61.6% decrease for individuals with hypercholesterolemia who do not attain low-density lipoprotein cholesterol and/or are intolerant to other lipid-lowering drugs.
Children Affected by Educational Disruptions Experience Mental Health Declines
During spring to fall 2020 related visits to emergency departments declined compared with a year earlier, study results show.
FDA Approves Purdue Pharma’s Nalmefene Hydrochloride Injection to Treat Opioid Overdoses
The agency has given the greenlight to the abbreviated new drug application for the overdose-reversal medication.
FDA Issues 3 Final Pieces of Guidance Regarding Oncology-Related Clinical Trials
The agency addresses the inclusion of older individuals in cancer-studies, the designing and conducting of multiple expansion cohorts, and the expedited development of biologics and drugs.
Keytruda Shows Hint of Major Added Benefit for Patients With Squamous Cell Carcinoma
The median survival time for individuals with SCC and treated with Merck’s pembrolizumab was 13.9 months compared with 8.8 months in the control arm.
Study: Structure of Clostridioides Difficile Provides a New Target for Future Treatments
Links of chain mail are arranged in the bacteria to form a pattern that prevents molecules from entering the cell.
AbbVie Announces Positive Results for Upadacitinib in Patients With Crohn Disease
The drug has achieved both primary endpoints of clinical remission and endoscopic response at week 12 compared with the placebo, the company says.
Studies Show Slightly Elevated Risk of Blood Clots Following COVID-19 Vaccine
The results of 2 analyses in the United Kingdom show a small increase in the potential for intracranial thrombosis after vaccination.
Bariatric Surgery May Reduce Breast Cancer Risk by Half
Results of studies show that women with obesity who get these weight loss procedures often also have preventative benefits.
Varicella-Zoster Vaccine Reduces Morbidity for Herpes Zoster, Postherpetic Neuralgia
The median duration of discomfort and pain was shorter in the vaccinated group than in the placebo group, at 21 days and 24 days, respectively, investigators say.
Study: Zip Codes Play a Role in COVID-19 Severity
Patients from more socially vulnerable areas were sicker when they arrived at hospitals but did as well as others by the time of discharge, results of a new analysis show.
AstraZeneca Announces Positive Results for Enhertu in Treating HER2 Breast Cancer
Trastuzumab deruxtecan demonstrated clinically meaningful and statistically significant improvements in overall and progression-free survival, the company says.