Ashley Gallagher, Associate Editor

Analysis finds that reported adverse events rarely led to the discontinuation of therapy when used as a migraine prophylaxis.

Latest results of the phase 3 IKEMA trial demonstrate the longest median progression-free survival on a proteasome inhibitor backbone in this population, Sanofi says.

The study marks the first time an albuterol/budesonide fixed-dose combination rescue medication has reduced severe exacerbations, the company said.

Independent committee recommends the phase 3 clinical trial continues to assess other primary and secondary endpoints for the treatment of unresectable or metastatic urothelial carcinoma.

Goal of modernizing therapeutic equivalence rating determination act is to increase availability, competition, drive down prescription costs.

Physicians often overlook those with lower BMIs who have nonalcoholic fatty liver disease and lower rates of other comorbidities, investigators say.

Analysis shows the activity of a specific enzyme, Butyrylcholinesterase, was significantly lower in those who subsequently died of sudden infant death syndrome.

Infections at community hospitals fell by 63% after 1 year and 77% after 3 years, new data show.

Individuals who have recovered from the initial disease are in generally poorer health later on compared with the general population, the analysis shows.

Investigators analyzed data from nearly 4000 individuals from the National Longitudinal Study of Adolescent to Adult Health.

The findings suggest that the broad use of race as a factor for providing certain health interventions and treatments should be reconsidered, investigators say.

Scientific abstracts also address findings on cardiovascular disease and population, the connection between COVID-19 and HF, and links between prognosis and marital status.

The advisory, published in Circulation, is a call to action for a cultural shift to identify and remove barriers.

Larger increases were typically seen in states with fewer deaths related to COVID-19, lower unemployment among women, analysis finds.

Long-term extension trial results show a consistent safety profile and durable efficacy for the treatment of adults with the skin condition.

A significantly greater proportion or patients treated with either 15 or 30 mg show remission or endoscopic response or remission at week 52 compared with the placebo.

The SKYSCRAPER-01 trial evaluating the drug plus Tecentriq demonstrates that it did not meet its co-primary endpoint of progression-free survival.

The results of a network analyses show that the elevated potential of contracting the virus is also linked to infliximab and tofacitinib, as well as several combination treatments.

Analysis also indicates that individuals with the highest-level beta-cryptoxanthin in their blood were less likely to develop cognitive issues decades later.

The recommendations apply to individuals who are already taking the maximum dose of statins.

Investigators develop a genetic-risk score to identify those who would benefit most from lifestyle counseling to prevent the condition.

Second analysis indicates that parents of children with food allergies became less anxious during the pandemic.

Students in the ISU/UAA pharmacy program discuss the impact of Alaska’s first pharmacy program and what it means to learn about and work in rural communities.

Analysis shows that half of individuals with both these sensory losses are cognitively impaired, investigators say.

Results from the DELIVER and DAPA-HF phase 3 trials demonstrate AstraZeneca’s Farxiga’s efficacy in heart failure, regardless of ejection fraction.

An international phase 1/2 clinical trial is ongoing for the treatment for individuals with relapsed or refectory acute myeloid leukemia with FLT3 mutation.

First phase 3 trial in this setting shows improved overall survival rates with an immunotherapy added to chemotherapy over the standard-of-care chemotherapy alone, company says.

Individuals who are not vaccinated with pre-existing diabetes, heart artery disease, or high blood pressure had a 2- to 3-fold increased risk of death, investigators say.

Spending 1 hour less sitting a day and increasing light physical activity helps prevent diseases, investigators find.

Individuals with college debt have a higher risk of cardiovascular illness, undermining the typical benefits of a post-secondary education, data indicate.