Ashley Gallagher, Associate Editor

Statistics indicate possible benefit of home-based palliative care interventions, according to study results from the Indiana University School of Medicine and the Regenstrief Institute.

Findings show that key factors include age, infecting variant, underlying illnesses, and vaccination status.

Palbociclib is indicated for adults in combination with an aromatase inhibitor as initial endocrine-based therapy in postmenopausal women or in men.

The drug combination achieved a median overall survival of more than 5 1/2 years in the first-line setting for postmenopausal women with HR+/HER2- aBC1, the company says.

Analysis results show taking iscosapent ethyl reduces the potential for CV death, coronary revascularization, hospitalization for unstable angina, myocardial infarction, and stroke by 35%.

The companies expect to complete the submission to the FDA for MDD in the first half of 2022 and an associated filing for postpartum depression in 2023.

Investigators find that 1 45-minute session of moderate intensity exercise allows more exosomes to deliver the protein, ATP7A, directly to endothelial cells, which can help enable angiogenesis.

This combination improves patient outcomes of vaccine-induced thrombotic thrombocytopenia after a COVID-19 vaccination, according to the results of a case analysis.

Discovery has the potential to also benefit treatment choices, investigators from Georgetown Lombardi Comprehensive Cancer Center say.

Results of a meta-analysis of randomized clinical trials published in JAMA shows improvement in 6 of 8 domains.

Data show that 89% of individuals treated for persistent AFiB remained symptom-free for up to 15 months after using the product.

Study shows that the vaccine candidate demonstrated superior neutralizing antibody titers over the control, Vaxzevria from AstraZeneca.

Clinical trial participants who took the drug lost up to 52 lb., or 24 kg, in the 72-week, phase 3 study.

Students from the University of the Sciences’ Philadelphia College of Pharmacy triumphed.

The advanced cell therapy is under development as an allogeneic hematopoietic stem cell transplant for patients with hematologic malignancies.

The company’s analysis shows data for the automated insulin delivery system for both T1D and T2D.

Data from the study shows a strong immune response in this age group following this dose, with no new safety signals.

FT218 is an investigational formulation of sodium oxybate that is designed to be taken once at bedtime for the treatment of excessive daytime sleepiness for individuals with narcolepsy.

Investigators observe strong immunogenicity profile in study participants aged 5 to 17 years 1 month after the primary vaccination series.

Individuals with diabetes, a higher body mass index, or a history of hospitalization are more likely to develop the condition, the analysis shows.

Of these visits, approximately 11%, or 8 million, resulted in antibiotic prescriptions, foremost commonly for illnesses that are not caused by a bacterial infection, such as bronchitis, non-bacterial skin conditions, and viral respiratory-tract infections.

STRIDE regimen of a single priming dose added to Imfinzi is the first dual immune checkpoint blockage regimen to improve overall survival in a phase 3 trial in this setting.

The PREVENT-19 study evaluates the immunogenicity and safety of a third dose of NVX-CoV2373 in children aged 12 to 17 years.

Intra Cellular Therapies’ Lumateperone is available in the 10.5- and 21-mg strengths and can also be used to treat depressive episodes associated with bipolar I or II disorder.

Belumosudil is indicated to treat individuals aged 12 years and older with chronic graft-versus-host disease who have received at least 2 prior systemic therapy treatments without success.

In a case study, the symptoms associated with the rash are fatigue, migratory lower extremity joint pain, and swelling of the ankles and feet.

ARCT-154 demonstrates 95% efficacy overall for prevention of severe disease, including related deaths.

Three in 5 say it is hard to get kids to eat well-balanced diets, because of not eating enough fruits and vegetables, pickiness, and other reasons.

FDA-approved Disulfiram can safely reduce anxiety levels in rodents, analysis from the Tokyo University of Sciences and other Japan institutes finds.

DuoBody, for treatment of relapsed/refractory large B-cell lymphoma, demonstrates an overall response rate of 63.1%.