Ashley Gallagher, Associate Editor

Investigators found that there was no association of dementia incidence in insulin use at 5 years after stopping metformin and an association at 0.07 years for HbA1C level at year 1.

In May 2023, the FDA approved brexpiprazole as the first and only drug to receive approval for treatment of agitation associated with Alzheimer Disease dementia.

Risk of atrial fibrillation with 1 of the independent predictors, including congestive heart failure and left atrial enlargement, resulted in greater than a 4-fold increased detection.

Pneumococcal serotype 3 was prevalent regardless of vaccination status, with the most common cases being in those with chronic lung disease.

In an article by The New England Journal of Medicine, the authors discuss how drug companies could delay the approval of new oncology drugs under the IRA, delaying patient care.

Without policies to reduce greenhouse gas emissions, the number of cardiovascular-related deaths due to extreme heat could even triple by mid-century.

Study also showed that 76% of individuals treated with lecanemab-irmb had no deterioration in the tau positron emission tomography (PET) subset.

Study finds that probable insomnia disorder was associated with physical health problems and difficulty with anger in veterans.

Arexvy shows efficacy in helping protect adults aged 50 to 59 years with an increased risk for respiratory syncytial virus lower respiratory tract disease.

Vosoritide is a daily injection for children with achondroplasia who have open epiphyses, given under the skin and administered by a caregiver.

BMS-986278 (Bristol Myers Squibb) is a potential first-in-class treatment for progressive pulmonary fibrosis and idiopathic pulmonary fibrosis.

Patients with HIV who were resistant to treatment with lenacapavir (Sunlenca; Gilead Sciences Inc) were found to have inadequate adherence to optimized background regimen or did not have a fully active antiretroviral.

This marks the first time that experts have defined cardiovascular-kidney-metabolic syndrome, including the overlap of cardiovascular disease with kidney disease, type 2 diabetes, and obesity.

Among individuals who received systemic antibiotics within 8 weeks, 6 months, 12 months, and 24 months of receiving fecal microbiota, RBX2660 prevented recurrence.

The biosimilar landscape is growing, but the FDA should leverage analytical data to efficiently determine the quality of these products and propel them toward approval, according to a session at the Academy of Managed Care Pharmacy’s Nexus 2023 conference.

Approximately 96% physicians feel it is important to assess patients aged 60 years and older for cognitive impairment, but 48% of these patients have no had assessments from their physician.

The FDA is the only authority that can designate a biosimilar as interchangeable with its reference product, which requires that the product has similar clinical results for the same indication.

There are 3 main medication-related issues for mental health care, which includes polypharmacy, nonadherence to prescribed medication, and underutilization of medications.

Areas of focus for specialty medications include biosimilars, cancer treatments, and drugs across disease states such as inflammatory conditions, HIV, and multiple sclerosis.

Artificial intelligence and machine learning can significantly benefit managed care pharmacy, specifically in contract reading and interpretation.

Obesity is a chronic disease comprised of dysregulated adipose tissue, increasing the risk of developing serious health conditions, and requires more than just losing weight.

Reform efforts to consider how health care plans may capitalize on disclosures, balancing out-of-pocket spending access, and how pharmacists can help plan members with the increased transparency of pharmacy benefit managers.

Although all legislation is currently on hold in Congress, there are important actions under consideration for pharmacy, including digital therapeutics, access to care, and health care disparities.

Investigators created a model to predict asthma exacerbations that can be integrated in WhatsApp chatbot and relies on self-reported data.

Many patients would like more education about managing their asthma, which can help to reduce the overuse of short-acting beta-2 agonists.

A study shows a significant increase in left ventricular ejection fraction when using pink noise stimulation with deep sleep.

SYNCHRONIZE-1, SYCHRONIZE-2, SYNCHRONIZE-CVOT will evaluate survodutide for overweight and obesity.

Black men had 27% lower odds of an ideal cardiovascular health score compared to White men, whereas Black women had 55% lower odds compared to White women.

Pharmacy Times will be providing exclusive session coverage and interviews with presenters for the Academy of Managed Care Pharmacy Nexus 2023 conference.

In the first systematic review using statistical methods, investigators found switching from a reference biologic to a biosimilar was comparable in safety, but no conclusion on immunogenicity could be drawn.