CLINICAL ROLE -
Dysbiosis in the Gut Microbiome May Lead to Development of Various Liver Diseases
There may be a pathophysiological basis for therapy relating to the to the gut-liver axis.
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Circadian Disruption May Be Significantly Linked to Chronic Kidney Disease
Increased waist circumference and high blood pressure can disrupt circadian rhythm, which can increase risk of progression to poor renal outcomes.
Fertility Preservation May Not Need to Delay Breast Cancer Treatment
Patients should work with clinicians to discuss controlled ovarian stimulation because there is still limited research.
Subcutaneous Daratumumab Plus VRd Significantly Improves PFS, Increases Depth of Response in Patients With Newly Diagnosed Multiple Myeloma
Data support the quadruplet regimen as a new standard of care for transplant-eligible patients.
Chlorine-Treated Drinking Water Might Change Species Diversity in Gut Microbiota
Findings from a recent murine model may translate to the human gut microbiome, but assessing chlorine’s effects on the gut microbiome remains complex.
Public Health Matters: A Review of Upcoming Digital Health Technology Products
Public Health Pharmacist discussed wearable technology and AI assisted technology that was displayed at the 2024 Consumer Electronics Show
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Exxua From Fabre-Kramer Pharmaceuticals
Generic Product News: January 2024
The products include Loteprednol Etabonate Ophthalmic Suspension, Teriparatide Injection, Allopurinol Tablets, and Sitagliptin Tablets.
RSV Vaccines See a Pricey Leap Forward in Disease Prevention
Older adults without a Part D plan face costs ranging from $180 to $295 per shot.
Triple-Negative Breast Cancer May Be Less Aggressive in Patients With SOX9-AS1 Overexpression
This RNA type might act as an onco-suppressor, and higher levels may indicate better prognosis.
Berberine May Reduce Inflammation of Lung Tissues in Patients With Metastatic Colorectal Cancer
Berberine was associated with a reduction in inflammatory markers in the lungs, which was caused by the colorectal cancer.
Three-Dose Hybrid Immunity Provided Older Adolescents With Robust Protection Against SARS-CoV-2 Infection
Infection-induced immunity with 2-dose vaccination still offered protection against the circulating variant.
Report: Oncology, Immunology Projected to Lead Global Spending From 2024 to 2028
The IQVIA Global Use of Medicines report for 2024 predicts that loss of brand exclusivity will negatively impact global market growth.
Study Findings Suggest Liver Creates Palmitic Acid, Maintaining Brain Health
The results from the preclinical trial can provide a new method of measuring dietary sources of nutrients in the tissue, but further research is needed to confirm the findings in the human brain.
ACIP Releases Updates On Vaccine Recommendations, 2024 Adult Immunization Schedule
The schedule includes RSV vaccination, along with updated versions of the COVID-19 vaccine.
Pharmacists Are Transforming and Optimizing HIV Treatment
Regardless of a pharmacist’s practice site or type, they play an integral role in ensuring the treatment success of patients with HIV.
Assessing Clinical Trial Efficacy vs Real-World Effectiveness in the Management of Multiple Myeloma
There is a significant efficacy-effectiveness gap in standard-of-care regimens.
Obstetrical Patient Dies After Inadvertent Administration of Digoxin for Spinal Anesthesia
The ampule of digoxin was accidentally taken from automated dispensing cabinet instead of bupivacaine
Early Experience Program Doses First Patient With Intravesical Gene Therapy at Urology Practice
Access to gene therapies can pose challenges for patients.
Rx Product News: January 2024
The products include Pilocarpine Hydrochloride Ophthalmic Solution 0.4%, Tenapanor, Zilucoplan, and Bimekizumab-bkzx.
Analysis Indicates Daily Multivitamin Benefits Global Cognition, Episodic Memory in Adults
Compared to placebo, a daily multivitamin showed consistent benefits in global cognition and episodic memory across a clinical trial and meta-analysis of 3 trials.
Implementing USP <800> Guidelines in Pediatric Hospitals
Protecting this vulnerable patient population requires specially designed strategies.
Updating Hospital Policies to Improve Inpatient Care for Patients With Parkinson Disease
Hospital pharmacists can play an important role in advocating for, designing, and implementing various policies to optimize care.
PQA Releases Third Edition of Social Determinants of Health Resource Guide
The third edition of the Pharmacy Quality Alliance resource guide includes 40 total SDOH services and 8 new services, as well as 10 initiative updates from the previous 2 editions.
Gender Gap in NIH-Awarded Research Grants Persists in the Field of Nonmalignant Hematology
Further policy changes to promote gender equity may be needed.
FDA Grants Fast Track Designation to Avutometinib Plus Sotorasib for Treatment of NSCLC
The treatment is for patients with KRAS G12C-mutant metastatic NSCLC who have previously received at least 1 systemic therapy and were not treated with a KRAS G12C inhibitor.
Clinicians Use SSRIs Off- Label in Many Conditions
As the body of data has grown, clinicians’ propensity to use selective serotonin reuptake inhibitors off-label has increased
All it Takes is a Conversation: Deprescribing Benzodiazepines in Older Adults
Benzodiazepines have proven effective in managing anxiety and insomnia, but they heighten risk of falls, cognitive impairment, functional decline, and mortality among older adults.
OTC Case Studies: Winter Colds
Standardized Onboarding Reduces Turnover of Pharmacy Technicians
The primary point of contact, called the Technician Success and Onboarding Coordinator (TSOC), is a new role created specifically to improve pharmacy technician retention.