CLINICAL ROLE -
Study Suggests BMI Does Not Indicate Length of Hospital Stay for Patients With Hypertension
Certain laboratory tests indicate stronger predictions for hospital stay, suggesting pharmaceutical intervention could help reduce the length of cardiovascular-related hospital stay.
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Cardiovascular Disease May Accelerate Tumor Growth in Patients With Advanced Breast Cancer
Patients with hormone receptor–positive and human epidermal growth factor receptor 2 breast cancer are particularly at risk.
Depemokimab Every 6 Months Reduces Rate of Severe Asthma Exacerbations
Investigators did not report serious adverse events or deaths related to depemokimab in either of the 2 phase 3a clinical trials.
Study Suggests Weakened RSV Vaccine Response in Immunocompromised Individuals
Immunocompromised older adults developed fewer antibodies against RSV following vaccination compared with immunocompetent individuals.
Equecabtagene Autoleucel Shows Efficacy, Safety in Treatment of Patients With Heavily Pretreated Multiple Myeloma
Patients with relapsed, refractory disease achieved deep, durable responses with equecabtagene autoleucel.
Majority of Children, Young Patients With Long COVID Recover Within 2 Years
Over 70% of children and young people with long COVID reported improvements in their symptoms within 24 months of their initial positive SARS-CoV-2 test.
Advise Patients to Use Caution When Purchasing Nootropic Agents Online
Although each of the product samples of phenibut contained the actual active ingredient, the exact amount of the active ingredient was inaccurate and, in one sample, found to be at a higher dose.
Novel Deep-Learning Model May Predict Immune Checkpoint Inhibitor Responses in Patients With Non−Small Cell Lung Cancer
The model, Deep-IO, shows improved specificity and sensitivity compared with existing predictive biomarkers.
MRX-5 Receives FDA Orphan Drug Designation for Treatment of Non-Tuberculous Mycobacteria Infections
The regulatory decision marks a significant step forward in the treatment of non-tuberculous mycobacteria infections.
Myelofibrosis Treatment Options: A Guide for Pharmacists
Treatment options may include treating the anemia with blood transfusions, androgen therapy, thalidomide, and other medications.
FDA Approves Tislelizumab in Combination With Chemotherapy for Gastric, Gastrosophageal Junction Adenocarcinoma
Tislelizumab is approved in combination with platinum and fluoropyrimidine-based chemotherapy as first-line treatment of unresectable or metastatic HER2-negative tumors.
ASHP Midyear: Pharmacists Play Key Role in Managing Chronic Kidney Disease With Emerging Therapies
Pharmacists can educate patients on controlling risk factors and stay up-to-date on emerging therapies like SGLT2 inhibitors and finerenone that can slow disease progression.
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FDA Approves Nivolumab and Hyaluronidase-nvhy for Subcutaneous Use in Patients With Solid Tumors
The approval offers patients with solid tumors an alternative to intravenous PD-1 inhibitor administration.
ASHP Midyear: Elevated Lp(a) Levels Pose Significant Cardiovascular Risk, Experts Emphasize Need for Awareness
Lp(a) is a critical risk factor for atherosclerotic cardiovascular disease, but current lipid-lowering therapies are largely ineffective at lowering Lp(a) levels.
Study Finds Nearly 75% of Adolescents Experience Depression, Anxiety
Female adolescents were at an increased risk of experiencing depression and anxiety symptoms compared with males.
ASHP Midyear: Bolus Dose of Antibiotic May Improve in Septic Shock
Administering first-dose antibiotics to septic shock patients via IV push rather than continuous infusion could improve the speed of antibiotic delivery and reduce logistical challenges.
Optimizing Delivery of Nimodipine in Patients With Subarachnoid Hemorrhage
This article is sponsored by Azurity Pharmaceuticals, Inc.
Because Ned Said: FDA Is Sued Over Removal of Blockbuster Weight Loss Drug From Shortages List
Some outsourcers and pharmacies have capitalized on the shortages, producing compounded versions.
Reimagining Established Drugs Medicines Could Lead to Potential New Applications
The potential treatments include ivermectin, methylene blue, glucagon-like peptide-1 receptor agonists, and low-dose naltrexone.
ASH 2024: Zanubrutinib Monotherapy, With Obinutuzimab Demonstrates Durable Efficacy and Safety in CLL/SLL
Constantine Tam, MD, discusses zanubrutinib's efficacy in CLL/SLL, emphasizing its durability, high response rates, safety considerations, and evolving therapeutic potential in combination with other agents.
MTM Updates Are Coming in 2025
Adding HIV/AIDS to core chronic diseases is a key change.
Advancing Lung Cancer Treatment With Bispecific Antibodies: A Review of Amivantamab and Tarlatamab
Bispecific antibodies amivantamab and tarlatamab hold promise for patients.
Black Patients With Asthma More Likely to Miss Scheduled Appointments for Biologic Therapies
The disparity highlights opportunities for pharmacists to get involved and address health disparities.
Patient Alleges Chain’s Opioid Policy Violates Antidiscrimination Statutes
Plaintiff argues that "blacklisting” certain individuals with opioid prescriptions was unlawful.
Transforming CLL Management: Pharmacists’ Impact on Treatment Strategies, Adherence, and Quality of Life
Anthony Perissinotti, PharmD, BCOP, discusses unmet needs and trends in managing chronic lymphocytic leukemia.
ASHP Midyear: Pharmacists Can Advocate for Expanded RSV Vaccination Recommendations
Pharmacists are crucial in educating patients, identifying eligible individuals, and promoting uptake of the newly expanded RSV vaccination recommendations for older adults.
Updated BNT162b2 XBB COVID-19 Vaccine Protects Against Hospitalization in Children Aged 5 to 17
Study results show that the updated BNT162b2 XBB vaccine is effective in preventing hospitalizations or emergency department visits associated with COVID-19 complications.
KRAKEN Trial Highlights Muvalaplin’s Efficacy, Safety in Reducing Lipoprotein(a)
Muvalaplin is an oral, small molecule inhibitor that can reduce lipoprotein(a).
Collective Responsibility, Confidence in Immunizations Indicate Potential of Vaccine Refusal
Individuals who refused a pneumococcal vaccine were associated with low collective responsibility and confidence in vaccine efficacy and safety.
Shaping the Future of Oncology Pharmacy Through the NCODA Medically Integrated Oncology Pharmacy Residency Program
The program develops patient-centered oncology pharmacists through comprehensive training.