Neurology

Pharmacists can make clinical recommendations tailored to patients’ individual needs.

Heart health may influence long-term brain health as early as middle age.

This social determinant of health could have the same level of negative impact on health as the experience of racism, poverty, or low education.

The drug can now be tested for safety, tolerability, and efficacy in a phase 1 study.

During the phase 1b/2 trials, CAR T-cell therapy demonstrated significant and clinical survival benefits.

Relapses of MIS-C occurred in 2 patients due to rapid tapering of corticosteroids at 2 weeks instead of the standard protocol of 4 to 6 weeks.

Advancements in the development of amyloid-targeting monoclonal antibodies show promise for treating Alzheimer disease, but there have been concerns around cost, adverse reactions, and inequity of care for marginalized patients.

Pharmacists play a key role in the management of modern monoclonal antibody treatments for Alzheimer disease.

Patient retraces her treatment journey from diagnosis through treatment for glioblastoma.

New anti-amyloid monoclonal antibody drugs for Alzheimer disease have produced encouraging results in targeting the accumulation of amyloid beta plaques; however, questions remain regarding the risk-benefit profile and cost implications.

Major pharmacogenomics organizations continue to recognize the potential relevance of pharmacogenomics for psychiatric medication management, mainly due to its effects on pharmacokinetics.

Idiopathic intracranial hypertension was previously considered a rare condition, however, its prevalence is increasing in parallel with obesity in patient populations.

Mobile apps can help consumers acquire medications, but few help with adherence beyond automatic refills or medication synchronization.

Participants were able to stop treatment after achieving amyloid plaque clearance and experience lasting results.

Study suggests supplemental oxygen may improve cognitive functions that are vital in motor learning, which can be important for people with neurological conditions or trauma.

Studies consistently demonstrate the pivotal involvement of neuropeptide calcitonin gene related peptide release in migraine onset.

Lecanemab-irmb is the first amyloid beta-directed antibody to be converted from an accelerated approval to a traditional approval for the treatment of Alzheimer disease.

The safety and efficacy of long-term benzodiazepine use beyond the recommended timeframe is not well understood.

The blood pressure drug could provide relief for veterans and service members suffering from traumatic brain injuries.

Despite prior studies showing less brain injury biomarkers in patients with targeted mild hypercapnia, findings from a new trial suggest it does not improve neurological outcomes at 6 months.

Galcanezumab-gnlm (Emgality; Eli Lilly and Company) did not demonstrate superiority to rimegepant orally disintegrating tablet (Nurtec ODT) on the percentage of individuals achieving a 50% or greater reduction in monthly migraine headache days.

Notably, donor hearts from those who underwent circulatory death were able to be preserved and analyzed in situ.

Access, diagnosis, and treatment for BIPOC patients suffering from migraines is yet another unflattering reflection of the lack of health equity in the United States.

As part of the approval condition, the FDA is requiring Sarepta Therapeutics to complete a clinical study to confirm the drug’s benefit in motor and physical functions.

Migraines can be a primary diagnosis or a symptom of an underlying medical or psychological condition.

Leqembi is an intravenous injection for the treatment of Alzheimer disease.

Standard prediction models that assess an individual’s risk of developing dementia and how to prevent it are limited in their ability to do so, showing high error rates and a higher chance of receiving a false-positive result, according to a recent study.

Heidi Finnes, PharmD, BCOP, FHOPA, addresses how the study data may impact the treatment of IDH1/2 mutating gliomas going forward.

Study evaluates the interaction between excessive salt intake and hypertension, cognitive dysfunction, and dementia.

Neuromyelitis optica spectrum disorder is an autoimmune disease characterized by severe attacks of optic neuritis and/or myelitis, leading to possible visual loss, paralysis, cognitive impairment, sensory deficits, bladder dysfunction, and even mortality.