Infectious Disease

Speaker Monica Diaz describes the detrimental impact climate change has on the transmission and increases in infectious disease cases.

The 5-in-1 meningococcal ABCWY vaccine candidate has an assigned Prescription Drug User Fee Act action date of February 14, 2025.

New indications include Staphylococcus aureus bloodstream (SAB) infections, acute bacterial skin and skin structure infections, and community-acquired bacterial pneumonia.

Scientists hypothesize that fecal microbiota transplant restores the recipient’s gut microbiota to an environment that mimics the healthy donor’s microbiota

The test scans whole blood samples from individual human donors for the 5 parasite species that can cause malaria in humans and detects Plasmodium RNA and DNA.

As data continue to develop in this arena, β-lactam therapeutic drug monitoring is likely to become more routine, as it has with drugs like vancomycin and the aminoglycosides.

Merck will also conduct clinical trials in both males and females to evaluate the efficacy of a single dose of their current human papillomavirus vaccine compared with the approved 3-dose regimen.

Study results indicate early swap to oral antibiotics in Staphylococcus aureus bacteremia is just as effective.

GBS can cause transcriptional adaptations, which may increase risk of poor neonate outcomes.

The regimen, which was used as second-line treatment in patients with drug-resistant TB, had a similar microbiological response to those with drug-sensitive TB taking first-line regimens.

Gepotidacin was compared with the combination of ceftriaxone and azithromycin in adolescent and adult patients with uncomplicated urogenital gonorrhea.

Malaria has a large global burden, affecting hundreds of millions of people each year.

Targeted use of ultraviolet light and sporicidal treatment can reduce disease transmission alongside existing interventions.

The researchers made a connection between positive outcomes for infectious disease patients, higher reimbursement class, and the presence of pharmacists in care teams.

Investigators found high incidences of non-susceptibility with penicillin and increasing resistance to macrolides for pneumococcal diseases.

Investigators from the University of Liverpool tested the effect of meropenem, an antibiotic used for hospital-acquired pneumonia, to determine how resistance emerges.

Creating a free app to assist in vancomycin dosing proved to be an entertaining and enlightening journey.

Older adults without a Part D plan face costs ranging from $180 to $295 per shot.

Those who were exposed to the clinically acquired stomach bacteria had a 24% increased risk of Alzheimer disease after a decade of onset.

The results have been highly anticipated, following other studies showing that doxycycline increased protection against sexually transmitted infections for cisgender men and transgender women.

The bacteria were shown to contain a membrane-bound organelle structure that is like those found in eukaryotic cells.

The approval marks isavuconazonium sulfate as the only granted azole antifungal therapy for pediatric patients with invasive aspergillosia and invasive mucormycotic who are as young as age 1.

In addition to growing rates of STIs, there is concern for antimicrobial resistance to STIs.

The approval marks the first authorized at-home sample collection test for sexually transmitted diseases.

The approval will benefit patients who have difficulty swallowing, dysphagia, or high taste sensitivities and struggle to adhere to the original antibiotic.

With the organism’s potential to cause severe symptoms, severe disease, and possible death, it is essential to care for infected individuals promptly and safely.

AI may help to significantly speed up drug discovery and development, and help researchers end the treatment-resistant infection crisis before it’s too late.

In a clinical trial, 2 vonoprazan-based regimens demonstrated higher rates of eradication as well as low rates of adverse effects compared to lansoprazole triple therapy.

Pre-exposure prophylaxis found to provide peace of mind for patients at risk of HIV, and coupled with frequent HIV testing in the health care setting, lowers the perceived risk of contracting the disease.

Parents are not fully educated on the risk of meningitis infection and preventive efforts for their children.