Heart Failure

The Phase 2 KARDIA-1 Study met its primary endpoint of lower systolic blood pressure with the use of zilebesiran.

Black women had the highest rates of obesity-related cardiovascular disease deaths whereas other racial groups had more men experiencing obesity-related CVD deaths than women.

Results from the VALOR-HCM LTE trial at 56 weeks demonstrated that with longer follow-up, mavacamten continued to reduce patient eligibility for invasive septal reduction therapy.

After 1 year of treatment, semaglutide significantly improved physical function, which can improve quality of life outcomes and risk of death.

Ferric carboxymaltose was not found to have a significant impact on 6-minute walk distance, which is part of the primary outcome’s hierarchical composite of death and hospitalizations from heart failure.

Stressful life events and poor sleeping patterns are linked to the development of atrial fibrillation in older women.

Pharmacists can actively engage in the implementation of the Comprehensive Diagnostics and Examinations in Acute Coronary Syndromes pathway within the hospital or health care system.

Notably, 65% of the participants experiencing pain at the 2-month follow up were also experiencing pain at their 12-month follow up, suggesting persistent and long-term pain.

Session at NACDS Total Store Expo discusses how pharmacies can leverage their accessibility to decrease diet-related diseases through health and wellness.

Research shows a substantial difference between overall deaths of men and women at 43% and 28.2%, respectively, from cardiovascular disease associated with particulate matter.

Study shows that as patients with type 2 diabetes lost more teeth, their risk of heart failure grew.

Updated guidelines, comprehensive review, and an investment of resources into pediatric preventive cardiology programs could help provide successful care.

Notably, patients with transthyretin cardiac amyloidosis had higher rates of heart failure hospitalizations, including patients treated with tafamidis.

Guidelines provide clear recommendation that oral transitional therapy is at least as effective as intravenous-only therapy for the treatment of infective endocarditis.

The lowering melatonin levels in patients with heart disease is one example of how heart conditions can influence systems throughout the body.

The risk of death from both overall and cardiovascular causes was also reduced in patients who underwent complete revascularization.

The risk could double if the conditions are met, with deaths more common in women and those aged 80 and older.

Pharmacists should provide guidance on issues such as proper drug disposal and potential drug interactions.

Quitting treatment may significantly improve severe hypertension in patients with hepatocellular carcinoma.

The risk of heart failure was higher in low- and middle-income countries when compared to high-income countries.

Population well-being was associated with cardiovascular disease morality and rates of conditions such as hypertension, diabetes, and obesity.

The novel treatment may be able to generate new cardiac tissue to create a functional human heart muscle.

An expert panel discussed the outreach of social determinants of health in community pharmacy care and how pharmacists can help patients find and access resources.

Patients with ST-segment elevation myocardial infarction who are uninsured were not found to be transferred between facilities at a higher rate than insured patients, and the amount of transfers were instead based more on the capability of a facility to provide percutaneous coronary intervention in a timely fashion.

Extended use of an N95 mask in daily life can cause various cardiopulmonary stresses, such as reduced respiration, elevated heart rate and blood pressure, and increased energy expenditure.

VALOR HCM is the second study to show that mavacamten can significantly reduce symptoms of obstructive hypertrophic cardiomyopathy, which includes left ventricular outflow tract.

STRONG-HF aimed to study whether rapid-dose escalation of guideline-directed heart failure medications was more beneficial than usual care.

Treatment with Injectafer significantly improved exercise capacity compared to placebo in a randomized clinical trial in adult patients with heart failure.

Management of heart failure focuses on avoiding reversible precipitants and optimizing guideline-directed therapy to lower mortality and hospitalizations.

Comprehensive in-hospital planning, postdischarge follow-up, ongoing support are key.