Digestive Health

The effects of probiotic strains on both constipation and cognition among all individuals involved in a meta-analysis remains difficult to determine.

Social jet lag could create adverse health impacts that a 90-minute difference in the mid-point of sleep can improve.

Therapeutic drug monitoring is a growing and vital area for pharmacists to become involved in to increase patient success with inflammatory bowel disease remission.

As more becomes known about Crohn disease, treatment modalities have evolved with biologic monoclonal antibodies becoming a key part of guideline- and evidence-based medicine.

In clinical trials of patients with Crohn disease, upadacitinib demonstrated early and long-term symptom relief, as well a visible reduction of damage to the intestinal lining caused by excess inflammation.

The sleep hormone decreased intestinal homeostasis, which may augment inflammation that causes tissue and intestinal damage.

As patents expire, the development of biosimilars may increase, opening up new opportunities to compare efficacies of these drugs.

Similarities between the symptoms of Clostridioides difficile infection and Crohn disease may cause confusion for health care providers.

The results of the INSPIRE trial demonstrated that 20.3% of individuals receiving risankizumab (Skyrizi) achieved clinical remission compared to 6.2% of individuals who received the placebo.

Different guidelines have notable differences between equivalency dosing of proton pump inhibitors (PPI), resulting in confusion and a lack of confidence between medical professionals recommending one PPI over another.

Purine metabolite xanthine, found in caffeinated beverages and food, affect cell differentiation, and new study results may lead to more knowledge about why diseases such as IBD develop.

Educate patients about the use of nonprescription products for digestive issues, and encourage them to seek further medical care when warrented.

Few Americans' diets meet the FDA's dietary guidelines; minerals and vitamins can pick up the slack to contribute to digestive health.

The popularity of intermittent fasting, or time-restricted eating patterns, may not help control weight as well as other dieting methods.

Products range from natural eye relief to sleep aid.

Analysis indicates that for individuals older than aged 40 years, the risk is cumulative and greatest 1 to 2 years after use.

Controlling blood pressure may be the most important type of treatment for vasculitis and lupus patients, said a professor of renal medicine at ASN Kidney Week in Orlando, Florida.

The relative abundance of gram-negative Bacteroidetes to other phyla, such as gram-positive Firmicutes, is essential to maintain biodiversity and human gut health.

Patients with type 2 diabetes may lower their risk of developing severe neurological disorders like Alzheimer disease by taking certain anti-diabetic medications alongside daily insulin.

In the trial, randomized patients with UC who received corticosteroids at maintenance baseline were able to eliminate the use of corticosteroids by week 200.

The VEGA study is the first randomized, controlled trial to evaluate the efficacy and safety of combination therapy with an interleukin (IL)-23p19 subunit antagonist (guselkumab) and a tumor necrosis factor-alpha (TNFα) antagonist (golimumab) in UC.

Sacrosidase was approved by the FDA to treat congenital sucrase-isomaltase deficiency, a condition that inhibits people from breaking down sucrose.

Ozanimod (Zeposia) is indicated for the treatment of multiple sclerosis and moderately to severely active ulcerative colitis in adults.

Risankizumab-rzaa is the first and only specific IL-23 inhibitor approved to treat moderately to severely active Crohn disease in adults.

Scientists found that inhibiting certain immune system receptors could treat colon cancer and other diseases of the gastrointestinal tract.