Specialty Pharmacy

Clinical trials are now evaluating the potential combination of PARP inhibitors with immunotherapy or other agents in patients with ovarian cancer.

Meaningful improvements in outcomes with immunotherapy in recent years are finally starting to change the tide for the first-line treatment of patients with small-cell lung cancer.

Merck has announced its plan to spin-off products from its women's health, trusted legacy brands, and biosimilars into a new, independent, and publicly traded corporation, according to the company.

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Treatment with niraparib resulted in a 38% reduction in the risk of disease progression or death in the overall study population compared with placebo.

Although the prevalence of health system-based specialty pharmacies has grown steadily over the past decade, 2020 will mark a critical year.

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With emerging research from The Sidney Kimmel Cancer Center-Jefferson Health, outcomes in patients with uveal melanoma that has metastasized were shown to significantly improve with changes in treatment.

In addition to safety and tolerability, a pair of clinical studies will evaluate the drug’s efficacy and ability to slow disease progression and to improve quality of life in patients with amyotrophic lateral sclerosis.

A study conducted by LSU Health found that by the time recommended screening for colorectal cancer begins, the disease has already spread in a high percentage of patients.

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Upadactinib met the primary endpoint for patients with active psoriatic arthritis who had responded inadequately or were intolerant to 1 or more non-biologic disease modifying anti-rheumatic drugs.

A new report from the Florida Pharmacy Association and American Pharmacy Cooperative, Inc, alleges that pharmacy benefit managers (PBMs) in the state are favoring their own affiliated pharmacies in the Florida Medicaid Program, both by driving customers to those pharmacies and by reimbursing them at higher rates.

As the industry focuses more on value-based care, predictive modeling allows pharmacies to shift their services from a one-size-fits-all approach to a personalized, high-touch strategy.

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New technique addresses the tendency of most CAR-T therapies to provoke immune responses against healthy tissues in patients.

Several viable models continue to emerge for addressing the unique challenges of payment and financing for innovative, durable, curative gene and cell therapies.

Not only is cancer control a matter of public health, but its value should be viewed as an investment with considerable human and economic returns, according to a newly released report from the World Health Organization (WHO). Furthermore, although disparities between cancer care in lower- and higher-income countries may seem overwhelming, the report emphasized that they are entirely solvable with effective national cancer control plans.

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The mechanism behind HIV resistance affects the ability of integrase strand transfer inhibitors to bind and block the HIV enzyme integrase.

Health systems, including inpatient and non-acute environments, will have a nearly 4% price increase for pharmaceutical purchases in the coming year, according to the report.

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Canakinumab, a fully human monoclonal antibody, targets interleukin-1β, has anti-inflammatory effects, and is FDA-approved for rheumatologic disorders. Interleukein-1β is a cytokine that drives the interleukin(IL)-6 signaling pathway in inflammatory response.

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As technology gains more of a foothold within the health care landscape, pharmacy professionals have an opportunity to harness the power of data and automatization.

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The decision is based on early academic clinical trial data that demonstrated ex-vivo autologous HSC gene therapy being an ideal approach for the treatment of X-CGD, a rare, life-threatening, inherited disease of the immune system.

Although there are no approved therapies for FSHD, researchers at Fulcrum Therapeutics discovered that inhibition of p38α/β reduced expression of the DUX4 gene in muscle cells derived from patients with FSHD.

Some REMS programs may only require a medication guide to be distributed with each dispense that highlight safety information, such as relevant adverse events and risks associated with taking the product.