Jill Murphy, Assistant Editor

The National DPP is an evidence-based lifestyle change program designed to delay or prevent the onset of type 2 diabetes among adults with prediabetes.

The study, which appears in The New England Journal of Medicine, is the largest to-date to compare thresholds for blood transfusions in premature babies, according to the press release.

A new thesis presented at Sahlgrenska Academy, University of Gothenburg, found that although immunizing children against chicken pox saves money, offering shingles vaccinations to all adults 65 years of age would not.

The objective of the study was to evaluate the impact of the ambulatory care pharmacist intervention on A1C changes in patients with uncontrolled type 2 diabetes mellitus (T2DM) during a 2-year period at the diabetes education center.

The research team designed TETi76 to replicate and amplify the effects of a natural molecule called 2-hydroxyglutarate (2HG), which inhibits the enzymatic activity of TET genes.

Decreases in prescription opioid volume over the past 9 years have been driven by changes in clinical use, regulatory, and reimbursement policies, and in progressively more restrictive legislation enacted since 2012.

The researchers familiarized mice with objects and gave them doses of melatonin and the 2 melabolites 1 hour later, followed by a test on their memory the next day.

Beta-carotene is the bioactive compound that gives carrots their orange color, with studies in humans and mice showing the conversion of beta-carotene to vitamin A as reducing bad cholesterol in the blood.

The papers in the special issue highlight the research team’s focus on understanding the experiences of caregivers of persons with TBI and illustrate the team’s ability to efficiently capture those experiences through a tool known as TBI-CareQOL Measurement System.

Monitoring outpatient prescribing patterns has been a major challenge for the Lifespan health system in Rhode Island, since it has over 1.5 million electronic prescriptions written annually.

Inhalation therapy is reliant upon correct inhaler technique to allow for optimal deposition of medication.

The objective of the study was to increase awareness among pharmacists about products for which unfounded claims have been made regarding prevention of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infections.

Specifically, in rural settings, growing primary care provider shortages impact patient access to care.

Acquired hemophilia A is a rare bleeding disorder caused by autoantibodies that inhibit coagulation factor VIII (FVIII), and the disorder is understudied given its rarity and the lack of randomized prospective trials to guide therapy.

ET and CT are used as standard maintenance therapy for HR-positive and HER-negative MBC in clinical practice, and there was no prospective study data on which is better, according to the study authors.

The update outlines that all 5 patients in the high dose 3 x 1013 vg/kg cohort have had at least 1 year of follow-up and showed sustained factor VIII (FVIII) activity levels, with a group median FVIII activity of 56.9% and a group geometric mean FVIII activity of 70.4% via chromogenic assay from week 9 to 52.

The objective of the study was to develop a method for de-escalation of intravenous (IV) vancomycin in patients receiving vancomycin with at least 1 other antibiotic appropriate for the treatment of community-acquired pneumonia (CAP).

The objective of the study was to quantify glucocorticoid dose-dependent cardiovascular risk in people with 6 immune-mediated inflammatory diseases.

Intravenous immunoglobulin administered to hypoxic non-ventilated COVID-19 patients with an A-a gradient of more than 200 mg Hg significantly decreases the rates of progression to mechanical ventilation.

Eligible patients in the APOLLO study had RRMM and received more than or equal to 1 prior line of therapy including lenalidomide and a proteasome inhibitor (PI) and had responded to prior treatment and progressed on or after their last regimen.

Melflufen plus dexamethasone as a triple regimen with bortezomib and daratumumab in patients with heavily pretreated relapsed or refractory multiple myeloma with poor prognostic factors was well-tolerated.

The combinations also demonstrated promising clinical activity, even among patients refractory to the last prior regimen and previously exposed to IMiD agents, proteasome inhibitors (PIs), and CD38 antibodies.

A recent nationwide survey of 400 pharmacists conducted by the American Pharmacists Association (APhA) found that more than three-fourths of pharmacists plan to be vaccinated with 1 of the coronavirus disease 2019 (COVID-19) vaccines.

Proteases are important to the health and viability of cells and viruses. If proteases are inhibited, cells cannot perform many important functions, such as replication.

The researchers launched the Perinatal Experiences and COVID-19 Effects Study to better understand the mental health and well-being of pregnant and postpartum individuals within the United States during the COVID-19 pandemic.

Further, the findings suggest that cancer survivors are also likely to be at an increased risk of severe coronavirus disease 2019 (COVID-19) outcomes, given that both influenza and COVID-19 are both epidemic respiratory viruses.

A recently published meta-analysis by the UConn Institute for Collaboration on Health, Intervention, and Policy (InCHIP) is the first-ever to explore the use of yoga, meditation, and mindfulness-based interventions for the effective treatment of chronic concussion symptoms.

The study showed that 95% of women who tested positive for COVID-19 during pregnancy had no adverse outcomes, with the virus being transmitted to the fetus in just 3% of the cases.

Examining several biomarkers to look for biological explanations for these results, the research team found key mechanisms, including insulin resistance, body mass index (BMI), lipoprotein metabolism, and inflammation, according to the study authors.

By volunteering with the American Red Cross, pharmacists can continue to help support communities who are struggling during the coronavirus disease 2019 (COVID-19) pandemic.