The Pharmacy Times® Oncology Clinical Role section is a comprehensive resource for clinical news and expert insights on issues pertaining to oncology pharmacists.
April 3rd 2025
Siremadlin is a novel, investigational, second-generation antagonist that binds to MDM2.
Introducing Tarlatamab-dlle: A New Era in Oncology Treatment
The therapy offers new hope in solid tumor treatment with fewer adverse effects.
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Review of 3 Alternative Pathways to Access Non–FDA-Approved Drugs
Non–FDA-approved medications may be accessed for patient care via 3 alternative pathways: expanded access, the Right to Try Act, and off-label use, which are reviewed in this article.
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Inotuzumab Ozogamicin in Pediatric Patients With Relapsed or Refractory B-Cell ALL
October 18th 2024This review discusses the significance of the FDA-approved drug inotuzumab ozogamicin in pediatric patients with acute lymphocytic leukemia (ALL) and relapsed/refractory (R/R) ALL, and the evolving therapeutic options in R/R ALL.
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Removing Mesna From Cyclophosphamide Cycles in VAdriaC-IE for Ewing Sarcoma
This retrospective cohort study provides preliminary evidence for safe removal of mesna from VAdriaC cycles, as the incidence of hemorrhagic cystitis did not increase in patients with Ewing sarcoma who received cyclophosphamide without prophylactic mesna.
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Revolutionizing Outpatient Oncology Care: The Seamless Integration of Artificial Intelligence
Artificial intelligence holds immense potential to address the rising demand for oncology services and improve patient outcomes by facilitating more effective, efficient, personalized cancer care.
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Brigimadlin: A Novel MDM2-Targeted Therapy for Dedifferentiated Liposarcoma
October 16th 2024The drug's safety profile included significant rates of nausea, vomiting, and hematologic toxicities like neutropenia and thrombocytopenia. Although promising, brigimadlin requires careful management of adverse effects, including antiemetic and hematologic support.
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