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The study authors suggest that after initiating alpelisib, patients should be proactive by improving glycemic status to reduce the risk of developing hyperglycemia.

Ruben A. Mesa, MD, FACP, discusses the results of the SIMPLIFY-1 and MOMENTUM trials and how the data led to the approval of momelotinib to treat intermediate or high-risk myelofibrosis in adult patients with anemia.

The FDA has issued a Prescription Drug User Fee Act fate of March 26, 2024, for sotatercept (Merck) as treatment for adults with pulmonary arterial hypertension.

Investigators also found that rates of type 1 diabetes have been on the rise since 2016.

Environmental factors may change sleep patterns over time, which subsequently affects rapid eye movement sleep.

Pharmacists are experts at juggling shortages of all kinds, however, and L’Altrelli said they are crucial team members regarding opioid access challenges.

Lutetium Lu177 dotatate demonstrated significant and clinically meaningful progression-free survival for those with SSTR-positive and inoperable midgut neuroendocrine tumor.

The combined enfortumab vedotin-ejfv and pembrolizumab treatment is recommended for patients with locally advanced or metastatic urothelial cancer who are ineligible for cisplatin-containing therapy.

At a 6-month follow-up, supplemental creatine intervention significantly improved scores for fatigue symptoms and tissue bioenergetics related to COVID-19 infection.

Study findings showed a 10% increase in the proportion of individuals staying home due to COVID-19 policy restrictions being associated with a 0.27 increase in PHQ-9 scores for depression.

Abrocitinib can reduce allergic responses in patients with a peanut allergy by decreasing cytokine activity and maintaining regulatory T cell activation.

The National Community Pharmacists Association said the action was sent into motion by wrongful penalties for Medicare Part D prescriptions, called pharmacy direct and indirect remuneration fees.

Bosutinib (Bosulif) is indicated to treat pediatric patients with Philadelphia chromosome–positive chronic-phase chronic myelogenous leukemia that is newly diagnosed, resistant, or intolerant to previous therapy.

Maintaining a purpose in life has the potential to reduce apathy related to dementia and cognitive decline.

Current federal statutes exclude anti-obesity medications for coverage when used for anorexia, weight loss, or weight gain.

Intravenous immunoglobulin found to provide fast and long-lasting relief for COVID-19-related neurological conditions, although investigators are still uncovering the pathology of many of these conditions.

Routine yoga therapy has shown endurance, strength, balance, symptom stability and quality of life improvements in individuals with heart failure.

A patient with lung adenocarcinoma who was treated with an immune checkpoint inhibitor developed symptoms related to asthma and breathing obstruction.

In clinical trials, lecanemab showed a reduction of amyloid beta plaque in patients with Alzheimer disease.

Functional exercise resulted in more improvements for individuals with PCC compared to standard treatment, although individuals must be monitored for adverse events.

Investigators reported that enfortumab vedotin-ejfv (Padcev; Astella Pharma Inc, Seagen Inc) in combination with pembrolizumab (Keytruda; Merck & Co Inc) met the dual primary endpoints of overall survival and progression-free survival in patients with previously untreated locally advanced or metastatic urothelial cancer.

Most patients had improved clinical response within 90 days of receiving the dendritic cell vaccine and ASCT.

As the resident medication experts, pharmacists are qualified to answer any medication-related questions and conduct data analyses.

Physical symptoms of burnout can include headaches, digestive problems, sleep disturbances, and increased susceptibility to illnesses due to a weakened immune system.

Datopotamab deruxtecan (Dato-DXd; AstraZeneca, Daiichi Sankyo) also demonstrated improved overall survival compared to chemotherapy.

An increase in cannabis use has led to growing concerns surrounding interactions between its components, THC and CBD, and prescription medications.

To promote positive mental health outcomes, researchers urge for policy interventions that focus on home connectedness, peer friendship, and school climate while avoiding full school closures.

Nivolumab has also demonstrated efficacy in immunotherapy-based combinations for the treatment of certain types of melanoma and bladder cancers.

Chemotherapy, medication for attention deficit/hyperactivity disorder, glucagon-like peptide-1 agonists for weight loss and diabetes, and local anesthetics were among the drugs most affected by shortages.

Empagliflozin (Jardiance) demonstrated a 28% relative risk reduction, with an absolute risk reduction of 3.6% per patient-year at risk in the treatment of chronic kidney disease.