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Researchers expect to file for FDA approval within the year following the successful phase 3 trial.

Receiving 3 doses of the COVID-19 vaccine can offer better and more long-lasting protection against the Omicron variant.

Fruquintinib reduced the risk of death in patients with advanced metastatic colorectal cancer by 34% and led to longer overall survival than among those given placebo.

Sunvozertinib is an oral, potent EGFR exon20ins inhibitor with wild-type EGFR selectivity.

But the 2021 modifications to the US Preventive Services Task Force recommendations do not eliminate the inequalities, analysis shows.

The findings also indicate that that treatment may have protective CV and limb benefits for those with kidney failure and concomitant peripheral artery disease.

Viral antigen levels in blood plasma can provide clinically important patient outcomes among hospitalized patients with COVID-19.

Prescription drug monitoring programs have decreased prescription opioids in the United States but resulted in unintended spikes of illegal drug use and heroin-related deaths.

The percentage of infections, hospitalizations, and deaths that were prevented from COVID-19 vaccination increased with greater vaccine coverage, according to a recent study.

Study suggests that myeloma patient survival after BCMA-targeted T-cell therapy could be determined by microenvironment factors.

Nintedanib is a tyrosine kinase inhibitor targeting key receptors involved in signaling pathways that led to pulmonary fibrosis.

Children younger than age 6 years might be protected from other COVID-19 variants for up to a year after infection.

Obesity, heavy alcohol consumption, and coagulopathy were some of the greatest risk factors associated with patients returning to the operating room within 48 hours of a surgery.

Pharmacists handle public vaccination efforts and need to assess where patients are on the hesitancy spectrum to provide reliable information.

New TROPiCS-02 data for Gilead treatment demonstrates progression-free survival benefit, regardless of HER2 status.

Patients should discuss efficacy and potential drug interactions with clinicians before use, study authors indicate.

The biosimilar is expected to be launched as a prefilled syringe in early 2023.

Dolutegravir is a more recently approved ART that is a part of a once-a-day regimen found to be more effective, easier to tolerate, and less likely to create new drug resistance in people with HIV-1 compared with other antiretroviral drugs.

Sacrosidase was approved by the FDA to treat congenital sucrase-isomaltase deficiency, a condition that inhibits people from breaking down sucrose.

A recent study suggests that infrequently taking non-steroidal anti-inflammatory drugs, especially ibuprofen, with type 2 diabetes can increase the risk of first-time heart failure and hospitalization.

A high proportion of myeloid cells may contribute to recurrence in those with long progression-free survival by promoting cancer growth and/or suppressing antitumor immunity.

Processed meats and products high in added sugars and low in fiber contribute to weight gain and obesity, which is an established risk factor.

Researchers suggest that dentists who do not administer antibiotics to high-risk patients for infective endocarditis could be risking the patient’s life.

Findings support the value of expanding this type of health care for patients with opioid use disorder.

Researchers suggest that understanding the incubation period of COVID-19 and its individual strains could determine the isolation period.

Complete recovery of platelet counts after obinutuzumab-based therapy was found to be associated with, or accelerated by, intravenous immunoglobulin.

Final analysis of phase 2 GRIFFIN study from the Johnson & Johnson subsidiary shows the combination demonstrates stringent complete response rate for transplant-eligible patients.

Pre-specified pooled analysis from phase 3 trials demonstrates 14% reduction in CV mortality and from any cause by 10% in individuals with HF, irrespective of ejection fraction.

A new statement from the American Heart Association stresses withdrawal medications and special care teams to prevent endocarditis in these individuals.

Results from the TOPAZ-1 phase 3 trial showed that the combination reduced risk of death by 20% versus chemotherapy alone.