Skylar Kenney, Assistant Editor

The investigators created a panel of pseudotype viruses, which combined the HIV virus and SARS-CoV-2 spike protein.

Concerns surrounding the vaccination of this population stemmed from the effects that cancer and its treatments can have on the immune system, but the investigators said this study should alleviate those fears.

The results of the study are consistent with several large-scale epidemiological studies that show an association between Parkinson and inflammatory bowel diseases, such as ulcerative colitis and Crohn disease.

Teclistamab is an off-the-shelf, T-cell redirecting, bispecific antibody targeting both B-cell maturation antigen (BCMA) and CD3 receptors.

The study also found significant variation in treatment of children and adolescents hospitalized with COVID-19.

This reduction in white matter has been well-documented, but the exact mechanism of action has been unknown until now, according to the study authors.

The use of IVIG in the treatment of recalcitrant pemphigus vulgaris and foliaceus and bullous pemphigoid is supported by 2 clinical trials.

The development of precision medicine for pancreatic cancer has faced a number of challenges, including a lack of specific molecular-targeted drugs.

Patients receiving dialysis are required to receive their treatments in clinics multiple times a week, meaning they were unable to effectively self-isolate.

Researchers found an association between fruit intake and markers of insulin sensitivity, which meant that people who consumed more fruit had to produce less insulin to lower their blood glucose levels.

The approval is based on a pair of Phase 3 studies in which oral ibrexafungerp demonstrated efficacy and a favorable tolerability profile in women with vulvovaginal candidiasis.

A recent study also found that weight loss may decrease dependence on medication.

The tool measures brain health based on cognitive performance and may be used in the future to predict the likelihood that an individual will develop memory and thinking problems as they age.

According to the study authors, 9% of the children receiving the combination therapy did not respond to treatment, compared to 51% of children receiving IVIG alone.

Adverse effects from intravenous immunoglobulin tend to be mild, but moderate and severe adverse effects have been observed.

The researchers analyzed immunization records for more than 300,000 Texas children from birth to 24 months.

Incidence rates of early-onset colorectal cancer in the United States have increased from 8.6 to 13.1 per 100,000 between 1992 and 2013, with most of this increase attributable to early-onset cancers of the rectum.

The researchers are hopeful this could eventually lead to the elimination of long-term antiretroviral treatment as a lifelong necessity for patients with HIV.

The goal of this year’s competition was to propose a technology-driven solution to address pandemics, mental health, or social determinants of health (SDOH).

New research results show that over the next decade COVID-19 may be more like the common cold.

A recent study found that nearly 3% of insured adults in the United States under the age of 65 years take medications that weaken their immune system.

A study published in Nature may document a previously unknown interaction between gut microbes and the thymus, an immune system organ.

Physical changes to DNA may contribute to greater inflammation and fatigue for these individuals.

According to the study authors, this model provides insights into the multiscale biological alterations in the elderly and neurodegenerative brain, which have important implications for identifying treatment targets for Alzheimer disease.

The investigators found that using the vaccine in combination with an immune checkpoint inhibitor—an established immunotherapy drug with a 20% success rate overall for patients—can vastly improve the proportion of individuals who respond to treatments, eliminating tumors in 75% of cases in mice.

Topline results from the phase 2/3 XIRIUS study of cotoretigene toliparvovec (BIIB112), a gene therapy being investigated as a one-time therapy for patients with X-linked retinitis pigmentosa (XLRP), found that the study did not meet its primary endpoint of demonstrating a statistically significant improvement in the proportion of treated study eyes.

The study authors said that treating the condition has been difficult until now due to a lack of FDA-approved therapies.

A combination immunotherapy of interleukin-21 (IL-21) and interferon alpha (IFN-alpha) in combination with antiretroviral therapy (ART) is effective in generating highly functional natural killer (NK) cells that can help control and reduce simian immunodeficiency virus (SIV) in animal models.

Smart agent systems designed to automate insulin dose selection for critically ill patients could potentially optimize the safety and efficiency of insulin infusion practices in intensive care unit settings, according to a study published in BMJ Quality & Safety.

Heart failure can involve multiple factors, but heart muscle scarring is thought to be an important contributing factor in up to two-thirds of patients with HFpEF.