Article

Researcher Awarded $7.5 Million in Funding for COPD Research

A researcher at the Washington University School of Medicine in St.Louis has received close to $7.5 million in total funding for research towards development of stem cell-based treatments for chronic pulmonary disease (COPD), asthma, and other disorders.

A researcher at the Washington University School of Medicine in St. Louis has received close to $7.5 million in total funding for research towards development of stem cell-based treatments for chronic pulmonary disease (COPD), asthma, and other disorders.

Michael J. Holtzman, MD, has identified a subset of stem cells that line in the airways, which are able to grow into other, more specialized types of cells. These cells can help drive mucus production in the lungs, making it crucial for an immune defense strategy.

The subset of stem cells become activated by common respiratory viruses and other inhaled agents, preventing airway injury and promote repair. Holtzman and his team are searching for therapeutic targets to control this stem cell response.

The grant will provide 7 years of funding for research towards these cells, as well as support ongoing efforts to identify pharmacological strategies for manipulating the stem cells.

Reference

Strait J. $7.5 million to fund pioneering approaches to respiratory disease [news release]. St. Louis, MO; September 9, 2019: WUSMSL website. https://medicine.wustl.edu/news/7-5-million-to-fund-pioneering-approaches-to-respiratory-disease/. Accessed October 11, 2019.

Related Videos
pharmacogenetics testing, adverse drug events, personalized medicine, FDA collaboration, USP partnership, health equity, clinical decision support, laboratory challenges, study design, education, precision medicine, stakeholder perspectives, public comment, Texas Medical Center, DNA double helix
Pharmacy, Advocacy, Opioid Awareness Month | Image Credit: pikselstock - stock.adobe.com
pharmacogenetics challenges, inter-organizational collaboration, dpyd genotype, NCCN guidelines, meta census platform, evidence submission, consensus statements, clinical implementation, pharmacotherapy improvement, collaborative research, pharmacist role, pharmacokinetics focus, clinical topics, genotype-guided therapy, critical thought
Hurricane Helene, Baxter plant, IV fluids shortage, health systems impact, injectable medicines, compounding solutions, patient care errors, clinical resources, operational consideration, fluid conservation, sterile water, temperature excursions, training considerations, patient safety, feedback request
Image Credit: © peopleimages.com - stock.adobe.com
Pharmacists, Education, Advocacy, Opioid Awareness Month | Image Credit: Jacob Lund - stock.adobe.com
TRUST-I and TRUST-II Trials Show Promising Results for Taletrectinib in ROS1+ NSCLC
World Standards Week 2024: US Pharmacopeia’s Achievements and Future Focus in Pharmacy Standards