Examining the 505(b)(2) Pathway and Implementation into EHR
March 20th 2025A panelist discusses how the 505(b)(2) regulatory pathway provides a streamlined approval process for modified versions of previously approved drugs, allowing pharmaceutical companies to rely partly on existing safety/efficacy data while still requiring new clinical data, commonly used across various therapeutic areas including reformulations, new dosage forms, and drug combinations.
Managing ADC Toxicities and Infusion Reactions With Supportive Care Strategies
March 20th 2025Panelists discuss how antibody-drug conjugates (ADCs) often cause toxic adverse events (AEs). Supportive care includes antiemetics, corticosteroids, and growth factors. Infusion reactions are managed with premedication and slow titration.
Strategies for Supporting Adherence to Treatment and Evaluating Efficacy
March 20th 2025Panelists discuss how health care professionals support medication adherence through personalized strategies, communication, and technological aids, while evaluating menopause therapy effectiveness via regular assessments, standardized tools, and comprehensive patient-centered approaches.
Patient Education When Initiating Treatment for Menopausal Symptoms
March 20th 2025Panelists note how medical professionals discuss menopause therapy, addressing symptoms, treatment options, safety concerns, adverse events, and personalized management strategies through patient-centered care. Professionals prioritize transparent communication, comprehensive risk assessment, and collaborative decision-making to ensure patient comfort and optimal management of menopausal transition.
Practical Insights for Pharmacists on ADC Administration, Patient Experience, and Supportive Care
March 20th 2025Panelists discuss how antibody-drug conjugates (ADCs) often show more diverse outcomes in real-world settings compared with clinical trials, with varying efficacy and adverse effect profiles. Key practical considerations for pharmacists include appropriate dosing based on patient factors, managing drug interactions, implementing premedication protocols to minimize adverse reactions, and providing comprehensive supportive care. Careful monitoring and individualized patient management are essential for optimal therapeutic outcomes.
Personalizing ADC Therapy in mBC Based on Patient Characteristics and Prior Therapies
March 13th 2025Panelists discuss how patient characteristics significantly impact antibody-drug conjugate (ADC) therapy selection, with key factors including the presence and location of brain metastases (due to blood-brain barrier penetration), organ function and comorbidities affecting toxicity risks, and prior treatment history that may influence both efficacy and safety. Treatment decisions require careful individualization.
Emerging ADC Clinical Trial Evidence in Breast Cancer Treatment
March 13th 2025Panelists discuss how emerging antibody-drug conjugates (ADCs) in metastatic breast cancer (mBC) treatment demonstrate innovation through optimized drug-to-antibody ratios, novel payloads, and targeted approaches to different breast cancer subtypes. Key trials explore combinations with established therapies and potential for improved tolerability profiles. Additional notable studies include comparative effectiveness research between approved ADCs and investigation of biomarker-driven patient selection strategies to maximize therapeutic benefit while minimizing adverse effects.
Dietary, Lifestyle, and OTC Approaches for Managing Symptoms of Menopause
March 13th 2025Panelists discuss how health care professionals recommend lifestyle modifications, dietary changes, and OTC products to manage menopause symptoms, focusing on exercise, nutrition, stress reduction, and targeted supplements to support overall well-being during this transitional period.
Counseling Patients About Pharmacologic Therapy for Menopausal Symptoms
March 13th 2025Panelists discuss how health care professionals develop personalized menopause management strategies by comprehensively assessing individual medical history, symptom profiles, lifestyle factors, and potential risks. Through transparent, collaborative counseling, they guide patients in making informed decisions about pharmacologic therapies, prioritizing personalized care and holistic well-being.
Wafa Samara, PharmD, Shares How Oncology Pharmacists Are Transforming Cancer Care at City of Hope
March 10th 2025Wafa Samara, PharmD, vice president and chief pharmacy officer at City of Hope, highlights the vital role of oncology pharmacists at City of Hope in improving patient outcomes, conducting and leading research, and working as integral members of the multidisciplinary care team.
Key Considerations for Oncology Pharmacists When Selecting and Sequencing ADC Therapies
March 6th 2025Panelists discuss how when making antibody-drug conjugate (ADC) treatment decisions for patients with metastatic breast cancer (mBC), pharmacists primarily consider patient-specific factors such as biomarker status, prior therapies, disease burden, and comorbidities. ADCs are typically introduced after standard first-line treatments show inadequacy or in specific molecular subtypes that demonstrate strong responses to targeted therapy.
Comprehensive Care for Women During Menopause: Addressing Bone Health and Cardiovascular Risk
March 6th 2025Panelists discuss how menopause care requires a holistic, patient-centered approach involving thorough medical assessment, interdisciplinary collaboration, personalized risk management, and comprehensive support addressing physical, psychological, and preventive health care needs.