Acalabrutinib Shows Significant Survival Benefit in Patients With Chronic Lymphocytic Leukemia
December 12th 2021The multicenter phase 3 study randomized patients with R/R CLL 1:1 to receive acalabrutinib 100 mg orally twice daily or investigator’s choice of idelalisib plus rituximab or bendamustine plus rituximab until disease progression or unacceptable toxicity.
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Expert Discusses Challenges, Risks of Ibrutinib as Chronic Lymphocytic Leukemia Treatment
December 12th 2021Lindsey Roeker, MD, assistant attending L1 at Memorial Sloan Kettering Cancer Center, discusses her ASH 2021 presentation and addresses some of the challenges and risk of ibrutinib as treatment for CLL.
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Ibrutinib, Venetoclax Combination Therapy May Provide Clinical Benefit to Certain Patients With CLL
December 10th 2021The combination therapy of ibrutinib and venetoclax was superior to chlorambucil and obinutuzumab in terms of undetectable minimal residual disease responses in elderly or unfit patients with previously untreated chronic lymphocytic leukemia.
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Herpes Zoster Occurs More Frequently in Certain Organ Transplant Recipients
December 10th 2021Although it was previously known that HZ incidence and HZ-related complications occur more frequently and with higher severity in solid organ transplant recipients, numbers varied extensively between studies.
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FDA Approves FoundationOne CDx as Companion Diagnostic for Melanoma
December 10th 2021FoundationOne CDx is a next-generation sequencing based in vitro diagnostic device for detection, insertion and deletion alterations, and copy number alterations in 324 genes and select gene rearrangements.
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Strategies for Solving Drug Therapy Related Problems in HIV Prevention Drugs
December 10th 2021In this video, Dr. Sherman recommends strategies for solving drug therapy related problems common to long-acting antiretroviral agents, such as missed doses, adverse drug reactions and drug–drug interactions.
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Efficacy, Safety of Current Treatments for C. Diff Infection, Recurrent C. Diff Infection
December 9th 2021Teena Chopra, MD, MPH, professor of infectious diseases at Wayne State University, discusses the current treatment strategies for C. diff infection and recurrent C. diff infection, as well as the efficacy and safety of these treatments.
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