CLINICAL ROLE -
Study Finds Increased Risk of Mental Health Disorders Following Cardiovascular Hospitalization
Risk of developing anxiety or depression is highest within the first year after cardiovascular hospitalization.
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Potential Role for IVIG in Treating Systemic Sclerosis With Muscular, Digestive Manifestations
The systematic review summarized all available evidence on the subject, finding that intravenous immunoglobulin could have a role in treatment.
Pharmacy Policy, August 2024
Conference Recap: McKesson ideaShare
FDA Approves Palopegteriparatide for Treatment of Hypoparathyroidism
Palopegteriparatide is a prodrug of parathyroid hormone designed to provide continuous exposure of the hormone over a 24-hour dosing period.
New Finding for Diabetic Wounds Has Potential for Use in Developing New Therapeutics
Many patients are unaware of wound complication, so it is valuable for pharmacists to communicate prevention methods with all patients with diabetes.
Color-Coded Asthma Medication Labels in Pharmacies Enhance Self-Management Education
Pharmacists played a crucial role in providing asthma action plans and enhancing patient education, despite challenges, and study limitations.
Study: Sales Price of Originator Declines After Introduction of Biosimilars
Investigators find that this could suggest the biosimilar uptake alone may not be a complete measure of the market competition and lowering prices.
Transforming Cancer Care: Innovations in Immunotherapy and the Critical Role of the Pharmacist
Pharmacists will play an integral role in this evolving field, from patient education and monitoring AEs to new therapeutic developments and treatment protocols.
The Expanding Role of Continuous Glucose Monitors in Pregnant Patients
The use of CGMs in pregnancy provides clinicians with essential data in real-time, rather than a snapshot given by traditional finger stick testing.
FDA Grants Rare Pediatric Disease Designation to SAT-3247 to Treat Duchenne Muscular Dystrophy
The commencement of the phase 1 clinical trial of SAT-3247 is expected in Q3 of 2024.
Finerenone Significantly Reduces Cardiovascular Death, Heart Failure in the FINEARTS-HF Trial
Non-steroidal mineralocorticoid receptor antagonist, finerenone, demonstrated improved efficacy compared with existing steroidal treatment for patients.
FDA Declines to Approve MDMA for PTSD
Previously, an independent advisory panel for the FDA rejected the use of MDMA-assisted therapy for posttraumatic stress disorder (PTSD), citing concerns of the reliability of the clinical trial data.
Hormone Therapy May Reduce Risk of Alzheimer Disease Pathology, Cognitive Decline in Women
Findings from 2 large datasets suggest hormone therapy may reduce Alzheimer risk, hippocampal atrophy, and cerebrovascular disease.
Clinical Presentation in Patients With Lymphoma Widely Vary, Making Treatment Difficult
A variety of signs and symptoms of lymphoma were reported, including fever, stomach discomfort, and weight loss.
New Study Assesses Ifinatamab Deruxtecan for Treatment of Small Cell Lung Cancer
The study is expected to include 460 individuals that will be randomly treated with 12mg of ifinatamab deruxtecan or chemotherapy chosen by the health care provider.
New Evidence Supports Cholesterol Absorption Inhibitors in Liver Cancer Prevention
Statins and non-statin cholesterol-lowering agents show potential in reducing the risk of liver cancer.
Research Demonstrates Asthma-Related Emergency Room Visits Increase During Peak Pollen Season
A number of asthma-related emergency room visits are a result of viruses, but certain airborne pollens—notably Cupressaceae and tree pollens—are also contributors.
Experts: Pharmacists Are Accessible and Valuable Resources in Arthritis Management
A clinical pharmacy specialist and specialty pharmacy manager from Allegheny Health Network urge patients to use their pharmacist in the treatment management of arthritis.
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The Role of Pharmacists in Addressing Patient-Specific Factors and Advancing CAR T Cell Therapy
Dan Schrum discusses the integral role of pharmacy specialists in translating clinical trial results to clinical practice.
Research Identifies Key Genes Linking Hashimoto Thyroiditis and Papillary Thyroid Carcinoma
The findings may lead to the development of diagnostic and therapeutic targets to prevent worsening disease in patients.
FDA Approves First Nasal Spray for Anaphylaxis
neffy is an epinephrine nasal spray for the emergency treatment of allergic reactions in adults and pediatric patients.
ABS-0871 Receives FDA Orphan Drug Designation for Treatment of Charcot-Marie-Tooth Disease 2C
The FDA also granted rare pediatric disease designation for the drug.
Community Pharmacy’s Existential Question: Chase Product Revenue or Service Margin?
Pharmacy is at a fork in the road. Business owners, investors, and (hopefully) practicing pharmacists will have a say in which direction the profession takes
QUILT 502 Trial Will Assess N-803 With AdHER2DC Vaccine for Patients With Endometrial Cancer
Investigators will examine the combination with pembrolizumab and lenvatinib in patients with HER2-expressing endometrial cancer.
Isatuximab Shows Promise in Enhancing PFS for Patients with Multiple Myeloma
Isatuximab (Sarclisa; Sanofi) in combination with standard-of-care significantly improved progression-free survival in patients with newly diagnosed multiple myeloma.
RHB-104 Plus Standard of Care Offers Extended Treatment for Crohn Disease
The primary end point of clinical remission at week 26 was met, with 36.7% of individuals treated with RHB-104 achieving clinical remission.
Intravenous Immunoglobulin Shows Safety and Effectiveness as Treatment of Pyoderma Gangrenosum
Intravenous Immunoglobulin as a therapy for patients with pyoderma gangrenosum could open new treatment avenues for the rare and challenging condition.
Tirzepatide Meets Both Primary End Points in Phase 3 SUMMIT Trial
Tirzepatide demonstrates statistically significant improvements in adult patients who have heart failure with preserved ejection fraction and obesity.
Insights into CAR T Cell Therapy Resistance: The Impact of the Tumor Microenvironment and T Cell Exhaustion
Dan Schrum highlights the crucial role of lymphodepletion in enhancing the effectiveness of CAR T cell therapy.