Oncology Overview: Investigational Imlunestrant for Breast Cancer, Endometrial Cancer
June 22nd 2022Imlunestrant is currently under investigation as monotherapy or in combination with other anticancer therapies for patients with estrogen receptor-positive, locally advanced or metastatic breast cancer and endometrial cancer.
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Kai Zhao, PhD, director of the Nasal Physiology and Therapeutic Center in the Department of Otolaryngology at Ohio State University College of Medicine, discusses how patients who have experienced a loss of taste and smell following COVID-19 infection may be impacted by this symptom for years without realizing it.
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The Role of Hospital Pharmacists in Administering and Supporting Immunizations in Health Systems
June 22nd 2022Vaccinations are a critical preventive vaccinations are a critical preventive health measure and are routinely recommended from an early age. Indeed, the first hepatitis B vaccine in the series can be administered within 12 to 24 hours of birth.
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Multiple Options Mean More Time for Patients With Indolent Lymphoma
June 21st 2022The treatment landscape for relapsed/refractory MZL and follicular lymphoma (FL) is shifting from intravenous chemotherapy and monoclonal antibodies to oral oncolytic therapy or CD19-directed chimeric antigen receptor (CAR) T-cell therapy.
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Opinion: The FDA is in a Hole With MOU on Compounding Medications—It Should Stop Digging
June 21st 2022Congress expected the FDA to draft a memorandum of understanding on interstate distributions of compounded medications that states would be willing to sign, but that’s not what the agency did.
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Investigators Report Series of Substates that Reprogram IgG to 1-Step Synthesis of gsADCs
June 20th 2022Glycosite-specific antibody‒drug conjugates (gsADCs), harnessing Asn297 N-glycan of IgG Fc as the conjugation site for drug payloads, usually require multi-step glycoengineering with 2 or more enzymes, which limits the substrate diversification and complicates the preparation process.
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