Common Manifestations of Congenital Plasminogen Deficiency
December 6th 2020Pharmacy Times® interviewed Charles Nakar, MD and Amy Shapiro, MD, of the Indiana Hemophilia & Thrombosis Center, on the common manifestations of congenital plasminogen deficiency, and whether it is life threatening for patients.
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Survival Estimates and Mortality Rates Among Patients With Polycythemia Vera
December 6th 2020Pharmacy Times® interviewed Brady Stein, MD, MHSc, of the Feinberg School of Medicine at Northwestern University, on the survival estimates for patients with polycythemia vera in the past and the mortality rates among these patients.
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Mortality and Causes of Death in Patients With Polycythemia Vera
December 6th 2020Pharmacy Times® interviewed Brady Stein, MD, MHSc, of the Feinberg School of Medicine at Northwestern University, on what polycythemia vera (PV) is and why it was important to understand mortality and causes of death among patients with PV.
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The Causes of Sickle Cell Disease and Beta-thalassemias
December 5th 2020Pharmacy Times® interviewed Christopher Moxham of Fulcrum Therapeutics, on what sickle cell disease and beta-thalassemias are caused by, and how hemoglobin gamma can prevent or reduce disease-related pathophysiology in these disorders.
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New Data on Gilteritinib in AML Presented at 2020 American Society of Hematology Annual Meeting
December 4th 2020Five oral presentations will include data on the use of gilteritinib, either as monotherapy or in combination, across the spectrum of patients with acute myeloid leukemia with a positive FLT3 mutation.
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Study: Patients With COVID-19 Should Continue Treatment With ACE Inhibitors, ARBs
November 19th 2020Results of a recent study confirmed that patients already taking angiotensin-converting enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) should not discontinue taking them due to COVID-19 infection.
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COVID-19 and Atrial Arrhythmias May Increase Risk of Major Adverse Cardiac Events, Death
November 18th 2020For patients with COVID-19, the combination of the disease and preexisting atrial arrhythmias may create a pathologic synergy that significantly increases the risk for major adverse cardiac events and death.
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Study: Children Exposed to Tobacco Smoke at Home Have Worse Heart Function as Adults
November 17th 2020The researchers examined the health records of more than 1100 adults, who had an average age of 45 years, were 52% female, and who are participants in the ongoing Childhood Determinants of Adult Health study.
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Survey Finds Lung Symptoms Common Among Users of E-Cigarettes, Related Products
November 13th 2020Researchers analyzed the survey responses of more than 1400 current users of e-cigarette and related products from 18 to 64 years of age, evenly divided among male and female, who took part in a national online survey in 2016.
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No Benefit to Postoperative Radiotherapy in Patients With Non-small Cell Lung Cancer
September 28th 2020At ESMO 2020, researchers discussed some long-awaited data regarding postoperative radiotherapy used in patients with non-small cell lung cancer following complete resection and after (neo) adjuvant chemotherapy.
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Among patients with cervical cancer, there was no significant difference found between the risk of recurrence, local recurrence, or death among individuals who either completed or abandoned a radical uterine procedure following the intraoperative detection of a positive pelvic lymph node.
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Study Finds Pembrolizumab Delivers Clinical Benefit in Selected Histotypes of Rare Sarcoma
September 24th 2020The results from a cohort of patients with rare sarcomas in the phase 2 study, presented by professor Jean-Yves Blay, MD, investigated the efficacy and safety of single agent pembrolizumab in rare cancers.
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Combination Therapy Not Found to Improve Progression-Free Survival in Ovarian Cancer
September 24th 2020Adding atezolizumab (Tecentriq) to bevacizumab (Avastin) and chemotherapy failed to significantly improve progression-free survival in patients with newly diagnosed stage III/IV ovarian cancer.
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Results of Phase 3 Study Find New First-Line Treatment Option for Metastatic Kidney Cancer
September 23rd 2020The CheckMate 9ER trial took 2 drugs used as monotherapies in the second line of therapy, nivolumab and cabozantinib, and combined them for use as a first-line treatment against standard of care, sunitinib.
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