CLINICAL ROLE -
FDA Update for Rheumatic Disease Drugs Presented at ACR Conference
FDA officials discuss safety data and drug approvals at the American College of Rheumatology Annual Meeting.
Rheumatologists Should Start Screening for Heart Disease
A significant portion of patients with rheumatoid arthritis may develop cardiovascular disease.
Immunotherapy May Increase Prevalence of Autoimmune Rheumatic Conditions
With the growing use of cancer immunotherapies, rheumatologists expect to see more cases of inflammatory conditions.
Osteoarthritis Phenotypes May Lead to Better Treatment Options
Patients with osteoarthritis may be able to receive targeted therapy based on phenotypes.
Baricitinib Data Suggests Long-Term Safety for Rheumatoid Arthritis
Major adverse cardiovascular event rates for baricitinib stabilize over time.
Tocilizumab Effective After Methotrexate Discontinuation
Methotrexate discontinuation was not observed to impact rheumatoid arthritis treatment with tocilizumab, according to an abstract presented at the 2017 American College of Rheumatology Annual Meeting.
Patients with Rheumatoid Arthritis May Need Additional Support to Reach Treatment Goals
Some patients with rheumatoid arthritis require a refined treat-to-target plan.
Protein May Not Differentiate Rheumatoid Arthritis, Hepatitis C Virus Symptoms
Low incidence of 14-3-3η in patients with long-term RA, chronic HCV with arthralgias.
Psoriatic Arthritis Therapy Affects Skin Involvement, Joint Severity
Treatment for psoriatic arthritis may impact symptoms and patient-reported outcomes.
Checkpoint Inhibitor Discontinuation May Not Be Necessary Due to Adverse Events
Flares and immune-related adverse events are common among patients with rheumatologic diseases but can often be successfully managed.
Improved Physician Education Needed to Curb Opioid Use for Juvenile Fibromyalgia
Study finds improved mental health resources and non-pharmacologic treatment options may be effective in reducing reduce opioid exposure among children with juvenile fibromyalgia syndrome.
How Disease Activity Affects Quality of Life in Patients With Psoriatic Arthritis
Patients with active psoriatic arthritis experience significant work instability based on disease activity.
Gout Research to be Presented at American College of Rheumatology Meeting
Study finds high unmet need among patients with uncontrolled gout.
Precision Medicine May Span to Autoimmune Disorders
Biomarker identification may improve abatacept (Orencia) treatment for rheumatoid arthritis.
Biologics, Triple Therapy a Good Follow-Up to Failed First-Line Methotrexate Treatment
Patients with rheumatoid arthritis who switched to biologics or triple therapy had a longer time to treatment failure versus augmented oral methotrexate.
Novel Model Addresses Care Gaps in Psoriatic Arthritis
Several modalities found to be effective in the triage of psoriasis patients with musculoskeletal symptoms, according to a study presented at the 2017 American College of Rheumatology meeting.
Investigational Drug May Treat Rare Skin Condition
Current treatment options for dermatomyositis may be ineffective for some patients, according to a study presented at the American College of Rheumatology Annual Meeting.
Investigational Drug Shows Efficacy as Disease-Modifying Therapy for Knee Osteoarthritis
Medivir to present positive data at the annual meeting of the American College of Rheumatology.
Real World Data in Rheumatoid Arthritis
Baricitinib significantly improved patient-reported outcomes in individuals with RA.
Psoriatic Arthritis Care Improving
New drugs for psoriatic arthritis discussed during a session at the ACR/ARHP conference.
Online Tools Improve Support for Teens With Juvenile Arthritis
At the Annual Meeting of the American College of Rheumatology in Washington, DC, several experts presented their progress in harnessing technology to help teenagers and young adults manage their juvenile arthritis.
Sarilumab vs Adalimumab: Which Provided Better Results Compared With Methotrexate?
Study compares the safety and efficacy of sarilumab with adalimumab in patients who cannot tolerate methotrexate.
How The Sunshine Act Affects Health Care
An ACR session focused on the Sunshine Act and health care transparency.
Rheumatoid Arthritis Paitents Unsuccessful on Methotrexate Achieve Surprising Results with Sarilumab
Sarilumab shows promise on circulating biomarkers of bone and joint destruction in patients with rheumatoid arthritis who had shown an inadequate response to methotrexate.
Claims-Based Analysis of Cost-Effectiveness of Cyclers vs Switchers in Patients With Less-Than-Adequate Tumor Necrosis Factor Inhibitors
Patients with rheumatoid arthritis who demonstrate a less-than-adequate response to a tumor necrosis factor inhibitor can be treated with another disease-modifying antirheumatic drug.
Following the Path of Antibody Structures to Biosimilars: A Journey in Innovation
Regulatory perspectives presented at ACR on biosimilars entering the market convey the importance of crafting antibodies to our own purposes.
Target-To-Treat Approach Beneficial for Rheumatoid Arthritis Treatment
New guidelines for rheumatoid arthritis treatment discussed at ACR conference.
Human Genome Could Lend a Hand in Creating New Rheumatoid Arthritis Treatments
ACR session reinforces the need for new research about how the genome, epigenome, and other factors play a role in rheumatoid arthritis.
Genes, the Environment, and Autoimmune Disease
There is building consensus that multiple sclerosis and rheumatoid arthritis display similar autoimmune genetic pathways.
Creating a Culture of Care Focused on Health, Not Illness
Clinicians who marry technical skills with humanities can see their patients and themselves in the larger context of family, society, history, politics, and economics.