Trending News Today: Tecentriq Safety Study Shows Positive Results in Bladder Cancer Patients

Roche’s atezolizumab (Tecentriq) demonstrated positive results in the phase 3b SAUL study in patients with metastatic bladder cancer, the largest safety study of its kind, according to a company press release. The study included approximately 1000 patients with locally advanced or metastatic urothelial carcinoma, including several clinically relevant populations reflective of real-world clinical practice. According to Roche, the data showed that both safety and efficacy, a secondary endpoint, were consistent with previous studies in both the overall population and a subgroup of patients corresponding to the patient population of the phase 3 IMvigor211 study.

A new study found that Apple Watch may be able to help detect atrial fibrillation (AF) in users, The Associated Press reported. The study included more than 419,000 Apple Watch users, of whom approximately 2100 participants were alerted by the watch to consult a study physician via telemedicine and wear an EKG patch measuring cardiac activity for the next week, the article reported. According to the preliminary study results, one-third of participants who underwent EKG monitoring had AF, and those who had another irregular heartbeat detection while wearing the EKG patch were more likely to have AF as well.

A recent report of data from previous studies indicates that consuming eggs may lead to an increased risk of heart disease, Reuters reported. According to the article, the analysis included 6 total studies involving 29,615 individuals who were followed for a median of 17.5 years and were asked to fill in questionnaires detailing food consumption. Over time, the researchers found there were 5400 cardiovascular-related adverse outcomes, including 2088 fatal and non-fatal heart disease events, 1302 fatal and non-fatal stroke events, 1879 fatal and non-fatal heart failure events, and 113 other cardiovascular disease deaths. Overall, the study suggested a 6% increased risk of cardiovascular disease when the average number of eggs consumed per day went up by half an egg, the article reported.