Shire names Bill Mordan General Counsel and Corporate Secretary; appoints Michele Galen Head of Communications and Public Affairs

PRESS RELEASE

Dublin, Ireland — June 15, 2015

— Shire plc (LSE: SHP, NASDAQ: SHPG) announces the appointment of Bill Mordan as General Counsel and Corporate Secretary, reporting to CEO Flemming Ornskov. Bill will also serve as a member of the Shire Executive Committee. He joins Shire from Reckitt Benckiser Group plc where he served as Group General Counsel and Corporate Secretary. Bill will join Shire following a notice period at Reckitt Benckiser.

“Bill joins as Shire’s General Counsel and Corporate Secretary at time when company is growing dynamically, enhancing its global reach and impact,” said Shire CEO Flemming Ornskov. “With his proven legal abilities, in-depth knowledge of the UK market, and experience advising management and the board, Bill brings a unique combination of technical and leadership skills that will help propel Shire to the next level.”

Bill joined Reckett Benckiser in 2003 as Area Vice President, North America. From 1997 to 2003, he worked for Procter & Gamble, holding diverse legal positions in Brazil, Mexico and the company’s corporate headquarters in Cincinnati, Ohio. Earlier in his career, Bill served as a law clerk in the U.S. Court of Appeals for the Sixth Circuit and taught high school in Bolivia. In 2014, his legal team at Reckitt Benckiser was recognized by the Financial Times as the Most Innovative In-House Legal Department. Bill graduated with a J.D. from the University of North Carolina at Chapel Hill, and a B.A. from the University of Notre Dame.

Shire also announces the appointment of Michele Galen as Head of Corporate Communications and Public Affairs, reporting to Flemming Ornskov. Michele will also serve as an extended member of the Shire Executive Committee. A lawyer and journalist, Michele most recently served as a Managing Director for MPM Capital and corporate advisor. From 2001-2014, Michele worked at Novartis in diverse leadership roles, including as the company’s Chief Communications Officer, based in Basel, Switzerland. Earlier, she worked as Managing Director for Burson-Marsteller, Editor for Business Week, and as an associate for Skadden, Arps, Slate, Meagher & Flom. Michele has a B.A. from George Washington University, J.D. from New York University School of Law, and M.S. in Journalism from Columbia University.

Both the General Counsel and Communications roles will be based at Shire’s US Operational Headquarters in Lexington, Massachusetts.