
|Articles|October 13, 2021
Pharmacy Clinical Pearl of the Day: Guillain-Barre Syndrome
Author(s)Saro Arakelians, PharmD
In its most severe form, Guillain-Barre syndrome is a medical emergency.
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Clinical Pearl of the Day: Guillain-Barre Syndrome
Guillain-Barre syndrome is a rare disorder in which the body's immune system attacks the nerves.
Insight:
- Weakness and tingling in the extremities are usually the first symptoms. These sensations can quickly spread, eventually paralyzing the entire body.
- In its most severe form, Guillain-Barre syndrome is a medical emergency.
- Most people with the condition must be hospitalized to receive treatment.
- Signs and symptoms of this syndrome include prickling; pins and needles sensation; weakness in the legs and unsteady walking; difficulty with facial movements, including speaking; double vision; severe pain that may feel achy; difficulty with bladder control; rapid heart rate; low or high blood pressure; and difficulty breathing.
- There are 3 types to this syndrome: acute inflammatory demyelinating polyradiculoneuropathy, Miller Fisher syndrome, and acute motor axonal neuropathy.
- Treatment options for this syndrome include plasma exchange (plasmapheresis), immunoglobulin therapy, pain relievers, physical therapy, and training with adaptive devices. This disease has no cure.
Sources:
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