Pharmacy Clinical Pearl of the Day: Guillain-Barre Syndrome

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In its most severe form, Guillain-Barre syndrome is a medical emergency.

Clinical Pearl of the Day: Guillain-Barre Syndrome

Guillain-Barre syndrome is a rare disorder in which the body's immune system attacks the nerves.

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Weakness and tingling in the extremities are usually the first symptoms. These sensations can quickly spread, eventually paralyzing the entire body.
In its most severe form, Guillain-Barre syndrome is a medical emergency.
Most people with the condition must be hospitalized to receive treatment.
Signs and symptoms of this syndrome include prickling; pins and needles sensation; weakness in the legs and unsteady walking; difficulty with facial movements, including speaking; double vision; severe pain that may feel achy; difficulty with bladder control; rapid heart rate; low or high blood pressure; and difficulty breathing.
There are 3 types to this syndrome: acute inflammatory demyelinating polyradiculoneuropathy, Miller Fisher syndrome, and acute motor axonal neuropathy.
Treatment options for this syndrome include plasma exchange (plasmapheresis), immunoglobulin therapy, pain relievers, physical therapy, and training with adaptive devices. This disease has no cure.

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