Daily Medication Pearl: Voriconazole (Vfend)

Medication Pearl of the Day: Voriconazole (Vfend)

Indication: Voriconazole (Vfend) is an azole antifungal indicated for the treatment of adults and pediatric patients 2 years of age and older with invasive aspergillosis and Candidemia in non-neutropenics and other deep tissue Candida infections.

Insight:

• Dosing: May start from 4 mg/kg/day and extend to 9 mg/kg/day based on the patient.
• Dosage forms: Tablets 50 mg, 200 mg.
• Adverse events: The most common adverse reactions (incidence ≥2%) were visual disturbances, fever, nausea, rash, vomiting, chills, headache, liver function test abnormal, tachycardia, and hallucinations.
• Mechanism of action: Voriconazole is an antifungal drug.

Source:

https://labeling.pfizer.com/showlabeling.aspx?id=618