Comprehensive Lancet Review Reaffirms Safety, Effectiveness of mRNA Vaccines
Messenger RNA vaccines were effective against any documented SARS-CoV-2 infection, against hospitalization, and against mortality within 14 to 42 days of vaccination.
A new review published in The Lancet has reaffirmed that currently approved messenger RNA (mRNA) vaccines remain safe and highly effective, drawing on data from billions of administered doses across diverse populations, including children, pregnant individuals, and immunocompromised patients. The analysis—led by investigators from the University of British Columbia and Imperial College London—pooled laboratory research, clinical trial results, and real-world surveillance data to evaluate the safety profile and the public health impact of mRNA vaccination since its emergency rollout during the COVID-19 pandemic.1,2