Publication
Article
Pharmacy Times
compounding HOTLINE
Author(s):
Mr. Erickson is director of professional affairs at Gallipot Inc.
Schamberg's Lotion was commercially availableat one time. We cannot find a source now.
Various formulations have been used. Accordingto Martindale, The Extra Pharmacopoeia, 27th ed:
Zinc oxide
8 g
Menthol
0.25 g
Phenol
0.5 g
Calcium hydroxide solution (lime water)*
46 mL
Olive oil qs ad
100 mL
Suggested Method of Preparation
*Prepare calcium hydroxide solution (saturated) prior touse. Combine 10 g with 1000 mL purified water by shakingwell; allow to stand covered overnight. Filter to remove theexcess. The solution should not contain <0.15% CaOH2.
- Calculate ingredient amounts required for the preparation.
- Weigh/measure ingredients.
- Dissolve the menthol and the phenol in the olive oil.
- Add calcium hydroxide solution; shake well to form an emulsion.
- Add the zinc oxide, stirring until smooth.
- If emulsion is not achieved and is desired, add 2 to 3 drops of Oleic acid and stir well.
Alternative Formulation, Medicated Emollient Suspension
Menthol
600 mg
Phenol
400 mg
Zinc oxide
20 g
Olive oil qs ad
120 mL
Calcium hydroxide solution (lime water)*
120 mL
(Note that total volume is >240 mL.)
Further modification increased the phenol concentrationconsiderably—"full-strength" Schamberg's Lotion has phenol4 g.
Package in tight, light-resistant containers. Label: "shakewell" and "external use."
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