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Glycosite-specific antibody‒drug conjugates (gsADCs), harnessing Asn297 N-glycan of IgG Fc as the conjugation site for drug payloads, usually require multi-step glycoengineering with 2 or more enzymes, which limits the substrate diversification and complicates the preparation process.

It is the role of the pharmacist to ensure patients are adequately counseled on the adverse effects and potential harms of codeine.

The topical therapy demonstrated significant improvements in the study, based on IGA success and other endpoints, according to investigators.

PrEP therapy has revolutionized HIV treatment by protecting patients who are high risk for acquiring the virus.

Risankizumab-rzaa (Skyrizi) is the first and only specific interleukin-23 inhibitor approved for the treatment of adults with moderately to severely active Crohn disease.

Contrave is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults.

Uqora Target flushes the urinary tract to help avoid urinary tract infections.

The treatment gives patients with neovascular age-related macular degeneration a more affordable option, the companies say.

The role of the pharmacist in sickle cell disease management revolves around appropriate pain management.

The study has met its primary endpoint, with approximately 78.4% of women who continued taking the drug achieving the sustained responder rate through week 76.

Anna Pham, PharmD, PGY2 ambulatory care resident at Intermountain Healthcare, discusses the role of ambulatory care pharmacists in primary care clinics.

Since the COVID-19 pandemic began, more than 10.6 million children have tested positive for the virus in the United States.

The drug is being evaluated as the first potential allogeneic advanced cell therapy donor source for patients with blood cancers in need of a transplant.

Utilization of the RAPID3 tool can be a beneficial way for pharmacists to complete disease activity assessments without physically seeing the patient in a clinic setting.

The ATHENA-MONO trial is investigating the use of rucaparib as front line maintenance treatment in ovarian cancer.

Biosimilar therapeutic interchange processes can mitigate high costs of cancer drugs.

Selpercatinib (Retevmo, Loxo Oncology) is FDA-approved to treat 3 types of tumors—metastatic RET fusion-positive non-small cell lung cancer, advanced medullary thyroid cancer (MTC) or MTC that has spread, and advanced RET fusion-positive thyroid cancer.

Jim Gilligan, PhD, discusses a phase 2 study investigating psilocybin-assisted therapy for binge eating disorder.

The Washington State Pharmacy employs technology for traditional dispensing and in Its compounding lab.

Clinically meaningful results may be a huge step forward in the development of a new therapy for systemic lupus erythematosus.

Over a period of 10 years, substituting antioxidants lutein and zeaxanthin for beta-carotene was found to be more effective at lowering the risk of AMD progression.

Buprenorphine (Butrans) is a partial opioid agonist indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment for which alternative treatment options are inadequate.

Cough suppressant and antihistamine lowers the frequency and intensity of coughing.

Aimee Banks, PharmD, BCPS, MSCS, clinical pharmacist in the Multiple Sclerosis Clinic at Vanderbilt University Medical Center, discusses the role of the pharmacists in patient care, improving outcomes, and managing transitions of care.

Paxlovid treats COVID-19 in adults who do not require supplemental oxygen and who are at an increased risk of progression to severe disease.

Expanded glomerular filtration rate (GFR) testing in the United States could be one step toward minimizing disparities in renal formulas, Beumer said.

There are more than 70 cases of monkeypox across 18 states in the United States, as of this week.

Pembrolizumab is an anti-PD-1 therapy that works by increasing the ability of the immune system to detect and fight tumor cells.

Although the COVID-19 pandemic saw the rapid hemorrhaging of women from careers in science and medicine, research shows the toxicity experienced by women may be structural in nature.

Trial court denial of claim Is pursued on appeal based on alleged error by judge when granting summary judgment.