CLINICAL ROLE -
Genetically Engineered CAR T Cells Serve as ‘Micropharmacies’ for Cancer Drugs
The novel CAR T cells can deliver a toxic drug payload directly to a tumor, killing tumor cells that contain the cancer marker and nearby cancer cells that do not.
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Study: Weight Loss Reduces Risk of Growths Linked to Colorectal Cancer
The research team suggests that healthy weight maintenance throughout adulthood is crucial in preventing colorectal adenoma.
Oncology Overview: Darolutamide, a New-Generation Oral Androgen Receptor Inhibitor
Darolutamide exerts its effects via competitive inhibition of androgen binding.
Jazz Pharmaceuticals Completes FDA Supplemental BLA for Rylaze Monday, Wednesday, Friday Dosing Schedule
The trial studied 3 dosing regimens of asparaginase erwinia chrysanthemi (recombinant)-rywn, with cohort 1a receiving 25 mg/m2administered Monday and Wednesday and 50 mg/m2administered on Friday.
In Memoriam: Michael J. Hennessy Sr.
Mike Hennessy was the beloved chairman and CEO of MJH Life Sciences.
The Value of Core Values in Pharmacy
Well-defined core values can take pharmacy operations to the next level.
Study Results Show Link Between Diabetes and High Blood Pressure
Investigators find that a small protein cell glucagon-like peptide-1 (GLP-1) couples the body’s control of blood sugar and BP.
Daily OTC Pearl: Remifemin
Remifemin provides an alternative to hormone replacement therapy for the treatment of menopausal symptoms.
Daily Medication Pearl: Armodafinil (Nuvigil)
Armodafinil and modafinil have wake-promoting actions similar to sympathomimetic agents.
Pharmacy Clinical Pearl of the Day: Granulomatosis
Granulomatosis is among a group of blood vessel disorders called vasculitis.
Expert Discusses Clinical Data That Show Trends in Mental Health Treatment
Stacy Miller, PharmD, BCPP, the senior content management consultant at Wolters Kluwer Health, discusses clinician search data focused on mental health treatment trends and needs.
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The Pharmacist's Role in Prior Authorizations
The prior authorization process often involves complex transactions and increases the burden not only on physicians and pharmacies, but can also impact patient access.
Study Results Link Social Determinants of Health to Increased Rates of Obesity
Limited empirical data from new study suggests correlations between obesity and individual SDOH, such as education level, food environment, income, and neighborhood.
Study Finds People with Depression May be More Susceptible to Misinformation About COVID-19 Vaccines
The research team found that levels of depression are at least 3 times higher than before the COVID-19 pandemic.
FDA Approves Cabenuva for 2 Month Dosing to Treat HIV-1
Medication can now be used as few as 6 times a year for virologically suppressed adults living with the disease without prior treatments not working or resistance to cabotegravir or rilpivirine.
Pharmacy Quiz: Test Your Knowledge on Atopic Dermatitis
Ten quiz questions to assess your knowledge on common symptoms and treatments for atopic dermatitis.
FDA Approves Vabysmo for Treatment of 2 Leading Causes of Vision Loss
Faricimab-svoa targets and inhibits 2 disease pathways that drive diabetic macular edema and neovascular or “wet” age-related macular degeneration.
Hospitalization Rates Increase for Uncontrolled Hypertension
Although men are more likely than women to be admitted for a hypertensive crisis, women have similar hospital mortality rates.
Daily OTC Pearl: OptiBalance
OptiBalance is a probiotic that helps at the start of menstruation to maintain a healthy balance.
Daily Medication Pearl: Bupropion (Aplenzin)
Bupropion (Aplenzin) is an antidepressant that treats major depressive disorder and seasonal affective disorder.
Pharmacy Clinical Pearl of the Day: Granuloma Annulare
Granuloma annulare is a skin condition that is not contagious and usually not painful.
2021: Pharmacists Are Moderately Satisfied With Salary, Job Satisfaction, Survey Shows (Part 2)
152 Respondents Rated Their Satisfaction With Total Annual Compensation 4.41 on a Scale of 1 to 7, Down From 4.82 in 2020
FDA Approves Label Update for Axicabtagene Ciloleucel for Improved Management of Cytokine Release Syndrome
Further, the 1-year update suggests that Cohort 6 toxicity management strategy can improve certain AEs without compromising the activity of axicabtagene ciloleucel.
With the 100-Year Anniversary of Insulin Discovery, Experts Look to the Future of Diabetes Care
Pharmacists are essential team members for the education of patients with diabetes, especially around injection technique for patients using injectable medications, such as insulin.
Study Finds Men with Anxiety May Develop More Risk Factors for Heart Disease, Stroke, Diabetes
The men were assessed for neuroticism—or the tendency to interpret situations as stressful, threatening, or overwhelming—and worry levels through 2 mail-in surveys.
How USP Is Working to Strengthen Global Supply Chain of Quality-Assured Medicines, Build Manufacturing Capabilities
Emily Kaine, MD, senior VP global health and manufacturing services at US Pharmacopeia (USP), discusses the work USP is engaged in to strengthen the global supply chain of quality-assured medicines and build manufacturing capabilities for new and innovative medicines.
FDA Issues Full Approval for Moderna COVID-19 Vaccine
The 2-dose Spikevax COVID-19 vaccine was approved by the FDA based on a comprehensive submission package including efficacy and safety data approximately 6 months after the second dose.
Research Finds Current COVID-19 Pills Effective Against Omicron, Antibody Drugs Less So
The pill molnupiravir and the intravenous drug remdesivir were just as effective against the omicron variant as they were against earlier strains.
COVID-19 Infection May Have Short-Term Impact on Male Fertility
But vaccines do not cause infertility or harm pregnancy chances, Boston University School of Public Health research results show.
Pet Peeves: January 2022
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