CLINICAL ROLE -
What to Do About Patiromer Drug Interactions
Hyperkalemia can be a persistent problem for a variety of patients, such as those with chronic kidney disease, diabetes, or heart failure.
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Do Warfarin and Sulfonylureas Interact with Each Other?
If the assumption is correct that warfarin and sulfonylureas are competing for the same binding sites, the order of drug administration might be an important factor determining the potential outcome.
Drugs Affecting Levothyroxine Absorption
A recent study assessed thyroidstimulating hormone and levothyroxine dosage in 5426 outpatients who had been prescribed levothyroxine, along with drugs that can impair levothyroxine absorption or affect levothyroxine metabolism.
Drug Interactions with CYP3A4: An Update
Absolute Versus Relative Risk
The results of a recent study suggest that there is a modest increase in the risk of intracranial hemorrhage when NSAIDs are combined with antidepressants compared with antidepressants alone.
Flibanserin: Hypotension and Syncope with Drug Interactions
Flibanserin (Addyi) has been approved by the FDA for the treatment of hypoactive sexual desire disorder in premenopausal women.
Milk Thistle Drug Interactions
Milk thistle is a herbal product widely used in the United States and around the world.
Edoxaban: A New Oral Factor Xa Inhibitor Anticoagulant
Edoxaban (Savaysa) has been approved for patients with atrial fibrillation.
Anticholinergic Drug Interactions
The potential dangers of the concomitant administration of 2 or more drugs with anticholinergic properties have been known for a long time.
Drug-Disease Interactions
It is possible for a precipitant drug to indirectly affect the object drug and for effective drug therapy to enhance the elimination of an object drug by treating a disease that inhibits drug elimination.
Drug Interaction Information: Too Many "Cooks"?
The process by which drug interaction information is generated, analyzed, and provided to health care practitioners is complex.
Evaluation of Drug Interaction Reports: Drug Dosing
The route of administration has been recognized as an important variable for drug interactions.
Warfarin Prescribed Despite Potentially Serious Interactions with Other Medications
Warfarin has been used for over half a century, and its interactions with other drugs have been exhaustively investigated.
Gastrointestinal Bleeding Due to Drug-Drug Interactions
The risk for upper gastrointestinal bleeding associated with the use of nonsteroidal anti-inflammatory drugs, corticosteroids, selective serotonin reuptake inhibitors, and antiplatelet drugs is well known.
Another Thiopurine-Allopurinol Tragedy
Drug Interactions with Marijuana
Codeine Drug Interactions
Prediction of Potential Drug-Drug Interactions
Extrapolating Pharmacokinetic Data to the Clinical Situation
Interactions with Hepatitis C Antivirals
Hyperkalemia from Drug Interactions: New Data
Statins and OATP Interactions
Is Acetaminophen a Problem in Hypertensive Patients?
A review of whether acetaminophen is likely to interact adversely with antihypertensive therapy.
Variability in Drug Interactions: Does a One-Size Dose Adjustment Fit All?
Serotonin Syndrome: Myths and Misconceptions
Serotonin syndrome was one of the first serious drug interactions ever described, with the first cases reported more than 50 years ago.
Kinase Inhibitors: An Update
Lomitapide Drug Interactions
Carboxylesterases and Drug Interactions
Incidence of Adverse Drug Interactions
One of the most problematic things about drug"drug interactions is that we seldom have data on how often a particular interacting drug pair causes adverse consequences.
Apixaban: An Oral Anticoagulant
Apixaban (Eliquis) was recently approved as an oral anticoagulant (a direct inhibitor of factor Xa) to reduce the risk of embolism in patients with atrial fibrillation.