Novel PCSK9 Inhibitor Recaticimab Lowers LDL-C in Adult Heterozygous Familial Hypercholesterolemia
September 12th 2025Recaticimab significantly lowered low-density lipoprotein cholesterol (LDL-C) levels, showing promise in becoming a future proprotein convertase subtilisin/kexin type 9 (PCSK9) option for cholesterol reduction.
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Expanding the Pharmacist’s Role in Myelofibrosis: Education, Adherence, and Access
Pharmacists play a crucial role in managing myelofibrosis, enhancing patient education, adherence, and financial navigation for optimal care.
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Decoding Most Favored Nation: Expert Insights on the Impacts to Patients, Pharma, and Innovation
A panel of 4 experts discussed the most favored nation (MFN) initiative and its impacts on research and development, market and payer distributions, and pharmacists and patients.
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Novel Conditioning Strategies Emerge in Gene Therapy, Leaving Busulfan—and Toxicities—Behind
September 12th 2025Speakers at an ASTCT Gene Therapy Summit highlighted novel conditioning approaches without the use of busulfan, which can cause toxic effects in patients with hematologic malignancies.
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FDA Expands Selumetinib to Children With NF1-Associated Plexiform Neurofibromas
September 10th 2025Selumetinib gains expanded FDA approval for younger pediatric patients with neurofibromatosis type 1 plexiform neurofibromas, enhancing treatment options and addressing significant disease-related challenges.
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PCV21 Shows Favorable Immunogenicity in Infants, Toddlers Receiving Pediatric Vaccines
September 10th 2025The 21-valent pneumococcal conjugate vaccine (PCV21) elicited favorable immunogenicity and safety in infants and toddlers who were coadministered common pediatric vaccines, such as the measles-mumps-rubella vaccine.
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Balancing Efficacy and Safety: Navigating Dose Adjustments and Therapy Optimization in Myelofibrosis
Jessica Lewis-Gonzalez, PharmD, BCOP, discusses the management of hematologic and non-hematologic toxicities in cancer patients, emphasizing the importance of proactive monitoring and collaboration between clinicians and pharmacists.
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Exploring the Antidepressant Potential of GLP-1 Receptor Agonists
GLP-1 receptor agonists show promise in alleviating depressive symptoms in patients with type 2 diabetes, offering a potential dual benefit in treatment.
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Aficamten Emerges as a Potential First-Line Therapy in Hypertrophic Cardiomyopathy
September 10th 2025Michael Fifer, MD, discusses the Maple HCM study, which compared the cardiac myosin inhibitor Aficamten and the beta blocker Metoprolol in patients with obstructive hypertrophic cardiomyopathy (HCM).
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