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Research Suggests Natural Supplementation Could Decrease Biological Age
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Key Takeaways
- Cel System targets biological aging mechanisms using plant compounds, vitamins, and antioxidants, addressing DNA instability, telomere shortening, and cellular senescence.
- A study with 51 participants showed improved grip strength, mobility, and body composition, alongside slower biological aging and altered immune cell composition.
A natural aging supplement enhances muscle strength and reduces biological age, promoting healthier aging.
A natural aging supplement, Cel System from Science Research Wellness (SRW), could impact the aging process by reducing biological age and improving muscle strength, according to findings published in the journal Aging.1
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Aging is the leading risk factor for disease, driving interest in interventions like genetic research and lifestyle changes to improve health span. As medical treatments improve, aging’s significant role in illness and death becomes more apparent. However, while the nutraceutical market is expanding, the study authors noted that while some supplements offer benefits, none are yet proven to slow or reverse biological aging.1
Cel System is a mix of plant compounds, vitamins, and antioxidants that forms a natural supplement designed to target the biological mechanisms linked with aging, explained experts in an accompanying news release.2
“The Cel System supplement range was formulated to target pathways associated with the Hallmarks of Aging when combining Cel1, Cel2, and Cel3 formulas,” the study authors noted in a news release.2
Cel1 adresses key drivers of aging, including DNA instability, telomere shortening, mitochondrial issues, cellular senescence, and chronic inflammation. Cel2 works in combination to target aging pathways linked to mitochondrial function, microbiome imbalances, stem cell vitality, and cell communication. Cel3 also focuses on cellular senescence, protein maintenance, and processes related to nutrient and cellular cleaning.1
Specifically, the Cel1 formulation contains 2-hydroxybenzylamine (hobamine), astragalus membranaceus extract (astragaloside), sophora japonica extract (rutin), vitamin C, levomefolic acid, vitamin B12, zinc, and selenium. The Cel2 supplement includes a blend of nicotinamide mononucleotide (NMN), pterostilbene, astaxanthin, L-carnosine, vitamin D, and riboflavin. Lastly, the Cel3 formula encompasses apigenin, fisetin, oleuropein, EGCG, berberine, alpha lipoic acid, and withaferin. The included ingredients combining all 3 formulas support healthy aging, brain function, DNA repair, and oxidative stress while also modulating immune function and gene expression and protecting cells from age-related stressors.1
To assess how the natural anti-aging supplement could influence the aging process, researchers from TruDiagnostic conducted a study to explore the effects of the supplement range on the clinical health and epigenetic age acceleration of healthy individuals that underwent supplementation for 12 months. A total of 51 individuals were included, 26 males and 25 females, aged 54.34 to 84 years. The researchers used DNA-based tests that analyzed methylation levels from blood and sputum tests that were administered at baseline, 3 months, 6 months, and 12 months. The tests aimed to track changes in biological age, physical performance, and body composition metrics. Individuals were instructed to walk for 10 minutes and practice mindfulness for 5 minutes daily in addition to taking Cel System.1,2
The results demonstrated that study individuals showed enhanced grip strength and mobility, along with reductions in body weight, waist circumference, and body mass index. These physical improvements coincided with slower biological aging, indicated by multiple epigenetic clocks, and a decrease in stem cell turnover. Additionally, the supplement also altered immune cell composition, suggesting a role in immune regulation during aging, and improved liver function biomarkers. Notably, inflammation markers remained largely unchanged.1,2
Further results demonstrated that at the molecular level, the supplement affected DNA methylation patterns linked to stress response, brain function, and cell communication, potentially underlying the observed physical and biological aging benefits.1,2
The findings suggest that Cel System supplementation supports individuals’ overall health by reducing signs of aging. However, the study authors noted that future randomized controlled trials with larger study groups are needed to confirm the results.1,2
